ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Chloropyrimidine 2,4-Dichloropyrimidine

2,4-Dichloropyrimidine

2,4-Dichloropyrimidine Basic information
Product Name:2,4-Dichloropyrimidine
Synonyms:2,4-DICHLOROPYRIMIDINE;2,6-DICHLOROPYRIMIDINE;2-4-DICHLOROPYRIMIDINE CRYSTALLINE;AKOS 91058;2,4-dichloro-pyrimidin;2,4-Dichlorpyrimidin;Pyrimidine,2,4-dichloro-;2,4-Dichloropyrimidine Pazopanib
CAS:3934-20-1
MF:C4H2Cl2N2
MW:148.98
EINECS:223-508-6
Product Categories:Building Blocks;Halogenated Heterocycles;Heterocyclic Compounds;Building Blocks;Heterocyclic Building Blocks;PyrimidinesHeterocyclic Building Blocks;Pyrimidine Series;Pyridines, Pyrimidines, Purines and Pteredines;Halides;Pyrazines, Pyrimidines & Pyridazines;Aromatics Compounds;Pyrimidines;Aromatics;Heterocycles;PYRIMIDINE;Pyrazines, Pyrimidines & Pyridazines;Heterocycle-Pyrimidine series;bc0001
Mol File:3934-20-1.mol
2,4-Dichloropyrimidine Structure
2,4-Dichloropyrimidine Chemical Properties
Melting point 57-61 °C (lit.)
Boiling point 101 °C/23 mmHg (lit.)
density 1.6445 (rough estimate)
refractive index 1.6300 (estimate)
Fp 101°C/23mm
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Powder, Crystals and/or Chunks
pka-2.84±0.20(Predicted)
color White to yellow to beige or grayish
Water Solubility Soluble in water (partly), methanol, chloroform, and ethyl acetate.
Sensitive Moisture Sensitive
BRN 110911
InChIKeyBTTNYQZNBZNDOR-UHFFFAOYSA-N
CAS DataBase Reference3934-20-1(CAS DataBase Reference)
NIST Chemistry ReferencePyrimidine, 2,4-dichloro-(3934-20-1)
EPA Substance Registry SystemPyrimidine, 2,4-dichloro- (3934-20-1)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-28A
RIDADR 1759
WGK Germany 3
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29335990
MSDS Information
ProviderLanguage
2,4-Dichloropyrimidine English
SigmaAldrich English
ACROS English
ALFA English
2,4-Dichloropyrimidine Usage And Synthesis
Chemical PropertiesWhite Solid
Uses2,4-Dichloropyrimidine was used in the synthesis of medicinally important 4-aryl-5-pyrimidinylimidazoles.
General Description2,4-Dichloropyrimidine is a human skin sensitizer. It undergoes effective one-pot, regioselective double Suzuki coupling reaction to yield diarylated pyrimidines.
2,6-Dichloropurine 4-Amino-2,6-dichloropyrimidine 97%,4-Amino-2,6-dichloropyrimidine ,97% 2,6,8-TRICHLORO-7-METHYLPURINE 2,4,5,6-TETRACHLOROPYRIMIDINE N1-(3-[(2,5,6-TRICHLOROPYRIMIDIN-4-YL)AMINO]PHENYL)-4-METHYLBENZAMIDE N-PHENYL-N'-(3-[(2,5,6-TRICHLOROPYRIMIDIN-4-YL)AMINO]PHENYL)UREA N1-(3-[(2,5,6-TRICHLOROPYRIMIDIN-4-YL)AMINO]PHENYL)-4-(TRIFLUOROMETHYL)BENZENE-1-SULFONAMIDE 5-Methyl-2,4-dichloropyrimidine 2,4-Dichloropyrimidine 2,6-Dichloro-7-methylpurine 2,4-Dichloro-6-methyl-5-nitropyrimidine 2,4,6-Trichloropyrimidine 2,4-Dichloro-6,7-dimethoxyquinazoline 2,6,8-TRICHLOROPURINE N1-(3-[(2,5,6-TRICHLOROPYRIMIDIN-4-YL)AMINO]PHENYL)-4-METHYLBENZENE-1-SULFONAMIDE 2,4-Dichloro-6-methylpyrimidine 2,4,6-TRICHLORO-5-NITROPYRIMIDINE 2,4-Dichloroquinazoline
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