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| | Catharanthine Basic information |
| Product Name: | Catharanthine | | Synonyms: | (+)-3,4-didehydrocoronaridine;18-beta)-lph;catharanthin;ibogamine-18-carboxylicacid,3,4-didehydro-,methylester,(2-alpha,5-beta,6-a;7-Ethyl-9,10,12,13-tetrahydro-6,9-methano-5H-pyrido[1′,2′:1,2]azepino[4,5-b]indole-6(6aH)-carboxylic acid methyl ester;Catharanthine, 98%, from Catharanthus roseus (L.) G. Don;4-Didehydrocoronaridine;methyl(2-alpha,5-beta,6-alpha,18-beta)-3,4-didehydroibogamine-18-carboxylate | | CAS: | 2468-21-5 | | MF: | C21H24N2O2 | | MW: | 336.43 | | EINECS: | 219-586-6 | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Heterocycles;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 2468-21-5.mol |  |
| | Catharanthine Chemical Properties |
| Melting point | 138-1400C | | alpha | D27 +29.8° (CHCl3) | | Boiling point | 472.9°C (rough estimate) | | density | 1.1367 (rough estimate) | | refractive index | 1.6500 (estimate) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO: soluble5mg/mL (clear solution; warmed) | | form | powder | | pka | 6.8(at 25℃) | | color | white to beige | | optical activity | [α]/D +30 to +38° (c=0.5, CDCl3) |
| | Catharanthine Usage And Synthesis |
| Chemical Properties | Off-White to Pale Beige Solid | | Uses | Precursor of Vinblastine-type alkaloids | | Uses | Anticancer | | Uses | Catharanthine is an indole alkaloid analog and an inhibitor of TRPM8. | | Definition | ChEBI: Catharanthine is an organic heteropentacyclic compound and monoterpenoid indole alkaloid produced by the medicinal plant Catharanthus roseus via strictosidine. It is a bridged compound, an organic heteropentacyclic compound, a methyl ester, a monoterpenoid indole alkaloid, a tertiary amino compound and an alkaloid ester. It is a conjugate base of a catharanthine(1+). | | target | NO | Calcium Channel | Nicotinic receptor |
| | Catharanthine Preparation Products And Raw materials |
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