| | N,N′-Diisoprophyl phosphordiamide fluoride Basic information |
| Product Name: | N,N′-Diisoprophyl phosphordiamide fluoride | | Synonyms: | Bisisopropylaminofluorophosphine oxide;Fluorure de N,N'-diisopropyle phosphorodiamide [French];Mipafox [ISO];N,N'-Diisopropil-fosforodiammido-fluoruro [Italian];N,N'-Diisopropyl-diamido-fosforzuur-fluoride [Dutch];N,N'-Diisopropyl-diamido-phosphorsaeure-fluorid;N,N'-diisopropylphosphorodiamidic fluoride;N-[fluoro-(isopropylamino)phosphoryl]propan-2-amine | | CAS: | 371-86-8 | | MF: | C6H16FN2OP | | MW: | 182.18 | | EINECS: | 206-742-3 | | Product Categories: | | | Mol File: | 371-86-8.mol |  |
| | N,N′-Diisoprophyl phosphordiamide fluoride Chemical Properties |
| Melting point | 65° | | Boiling point | 125.5°C | | density | 1.2 g/cm3(Temp: 25 °C) | | pka | -2.71±0.70(Predicted) | | form | solid | | Water Solubility | 74.07g/L(temperature not stated) | | EPA Substance Registry System | Mipafox (371-86-8) |
| Hazard Codes | T+ | | Risk Statements | 39/26/27/28 | | Safety Statements | 13-45 | | RIDADR | 2783 | | HazardClass | 6.1(b) | | PackingGroup | III | | Hazardous Substances Data | 371-86-8(Hazardous Substances Data) | | Toxicity | Formerly used as a
systemic insecticide. Its use was discontinued because of
severe delayed neuropathy hazard in humans. The oral
LD50/LC50 in rabbits is 100 mg/kg. Toxic action is as a neurotoxicant
with both acute and delayed actions, acting as a
cholinesterase inhibitor (acute toxicity) and as a neurotoxic
esterase inhibitor (possibly linked to delayed toxicity).
Symptoms in humans are typical anticholinesterase symptoms.
Therapy is supportive as well as atropine sulfate and
2-PAM. |
| | N,N′-Diisoprophyl phosphordiamide fluoride Usage And Synthesis |
| Uses | Insecticide. | | Uses | Mipafox is an insecticide. | | Definition | ChEBI: Mipafox is a phosphoramide. | | Hazard | Cholinesterase inhibitor. | | Safety Profile | Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of F-, NOx, and POx. See also PARATHION and FLUORIDES. |
| | N,N′-Diisoprophyl phosphordiamide fluoride Preparation Products And Raw materials |
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