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| | Fluclotizolam Basic information |
| Product Name: | Fluclotizolam | | Synonyms: | 2-chloro-4-(2-fluoro-phenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, 2-chloro-4-(2-fluorophenyl)-9-methyl-;Fluclotizolam | | CAS: | 54123-15-8 | | MF: | C15H10ClFN4S | | MW: | 332.78 | | EINECS: | 200-284-8 | | Product Categories: | | | Mol File: | 54123-15-8.mol |  |
| | Fluclotizolam Chemical Properties |
| Boiling point | 524.0±60.0 °C(Predicted) | | density | 1.57±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMF: 5 mg/ml DMSO: 5 mg/ml DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml | | pka | 2.01±0.40(Predicted) | | form | A crystalline solid | | λmax | 241 nm | | InChI | InChI=1S/C15H10ClFN4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)17)10-6-12(16)22-15(10)21(8)13/h2-6H,7H2,1H3 | | InChIKey | ZDYRCUZZLRLMHG-UHFFFAOYSA-N | | SMILES | N12C(C)=NN=C1CN=C(C1=CC=CC=C1F)C1C=C(Cl)SC=12 |
| | Fluclotizolam Usage And Synthesis |
| Description | Fluclotizolam (Item No. 23524) is an analytical reference standard categorized as a thienotriazolodiazepine. This product is intended for research and forensic applications. | | Chemical Properties | Flualprazolam (8-chloro-6-(2-fluorophenyl)-1-methyl-4H- [1,2,4]triazolo[4,3-a][1,4]benzodiazepine) is a triazolobenzodiazepine and is structurally similar to alprazolam. Flualprazolam is composed of a benzene ring fused to a seven-membered 1,4- diazepine ring. Flualprazolam also contains a fused triazolo ring. A methyl (-CH3) group is attached at the 1-position, a 2- fluorophenyl ring is attached at the 6-position, and a chlorine is attached at the 8-position of the triazolobenzodiazepine structure. Flualprazolam has a molecular formula of C17H12ClFN4 and a molecular weight of 326.76 g/mol. | | History | Fluclotizolam is a thienotriazolodiazepine derivative which was first synthesised in 1979, but was never marketed. It has subsequently been sold as a designer drug, first being definitively identified in 2017. | | Uses | Fluclotizolam is one of the New Psychoactive Substancces (NPS). | | Side effects |
Fluclotizolam produces a sedative-hypnotic effect, often causing drowsiness, muscle relaxation and slowed, sluggish reactions.
| | Regulatory Status | Flualprazolam is not currently controlled under the Controlled Substances Act. At the 2020 Commission on Narcotic Drugs Sixty-third session, the Commission decided to include flualprazolam in Schedule IV of the 1971 Convention on Psychotropic Substance.
https://www.deadiversion.usdoj.gov
https://www.federalregister.gov | | References | 1. Moosmann, B., and Auw?rter, V. New Psychoactive Substances. Handbook of Experimental Pharmacology. Designer benzodiazepines: Another class of new psychoactive substances 252, 383-410 (2018). |
| | Fluclotizolam Preparation Products And Raw materials |
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