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| | SPINOSAD Basic information |
| Product Name: | SPINOSAD | | Synonyms: | Mixture of Spinosyn A and Spinosyn D;Spinosad [iso];Tracer naturalyte;SPINOS;Spinosad Standard;Spinosad @100 μg/mL in Acetonitrile;Spinosad@1000 μg/mL in Acetonitrile;Spinosad (Mixture of Spinosyn A and Spinosyn D) | | CAS: | 168316-95-8 | | MF: | C41H65NO10 | | MW: | 731.96 | | EINECS: | 605-513-9 | | Product Categories: | Miscellaneous Natural Products | | Mol File: | 168316-95-8.mol |  |
| | SPINOSAD Chemical Properties |
| Melting point | 110℃ | | storage temp. | 0-6°C | | solubility | Ethanol: 1 mg/ml | | form | neat | | EPA Substance Registry System | Spinosad (168316-95-8) |
| Hazard Codes | N | | Risk Statements | 50/53 | | Safety Statements | 61 | | RIDADR | UN3077 9/PG 3 | | WGK Germany | 3 | | Toxicity | LD50 in rats, mallard ducks, quail (mg/kg): >3600, >2000, >2000 orally (Crouse) |
| | SPINOSAD Usage And Synthesis |
| Description | Spinosad is a naturally-occurring insecticide found in the the soil bacterium S. spinosa. It is a mixture of the macrocyclic lactones spinosyn A and spinosyn D , which act as agonists of insect nicotinic acetylcholinesterase receptors (nAChRs). Oral administration of spinosad induces toxicity in fruit flies including C. capitata, B. curcurbitae, and B. dorsalis (LC50s = 2.8-4.2, 4.3-5.5, and 3.1-3.3 μg/ml, respectively) but has low toxicity in vertebrates. It also inhibits canine P-glycoprotein (P-gp; IC50 = 0.2 μg/ml). Formulations containing spinosad have been used in the agricultural and veterinary control of insects. | | Uses | Insecticide. | | Definition | Isolated from Saccharopolyspora
spinosa (Actinomycetes).
| | Hazard | A poison by inhalation. Moderately toxic
by ingestion.
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| | SPINOSAD Preparation Products And Raw materials |
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