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| | 2-Chloro-5,6,7,8-tetrahydro-pyrido[3,4-d]pyriMidine Basic information |
| Product Name: | 2-Chloro-5,6,7,8-tetrahydro-pyrido[3,4-d]pyriMidine | | Synonyms: | 2-Chloro-5,6,7,8-tetrahydro-pyrido[3,4-d]pyriMidine;Pyrido[3,4-d]pyrimidine, 2-chloro-5,6,7,8-tetrahydro- | | CAS: | 1196153-06-6 | | MF: | C7H8ClN3 | | MW: | 169.61 | | EINECS: | | | Product Categories: | | | Mol File: | 1196153-06-6.mol | ![2-Chloro-5,6,7,8-tetrahydro-pyrido[3,4-d]pyriMidine Structure](CAS/20150408/GIF/1196153-06-6.gif) |
| | 2-Chloro-5,6,7,8-tetrahydro-pyrido[3,4-d]pyriMidine Chemical Properties |
| Boiling point | 356.8±32.0 °C(Predicted) | | density | 1.297±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 6.80±0.20(Predicted) |
| | 2-Chloro-5,6,7,8-tetrahydro-pyrido[3,4-d]pyriMidine Usage And Synthesis |
| Description | 2-Chloro-5, 6, 7, 8-tetrahydro-pyrido [3, 4-d] pyrimidine is a deriviative of pyrimidine. 5, 6, 7, 8-tetrahydropyrido[3, 4-d] pyrimidine compounds can act as mTOR kinase and PI3 kinase inhibitors and be used in the treatment of related metabolic diseases. It can also inhibit the extracellular signal-regulated kinase (Erks), and thus have potential to assist in the treatment of related tumor.
| | References | https://www.mendeley.com/research-papers/5678tetrahydropyrido34dpyrimidine-compounds-mtor-kinase-pi3-kinase-inhibitors-preparation-treatment/
Blake, J. F., et al. "Discovery of 5, 6, 7, 8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2. " Bioorganic & Medicinal Chemistry Letters 24.12(2014):2635-2639.
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| | 2-Chloro-5,6,7,8-tetrahydro-pyrido[3,4-d]pyriMidine Preparation Products And Raw materials |
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