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| | (+)-SYLVATESMIN Basic information |
| Product Name: | (+)-SYLVATESMIN | | Synonyms: | Philligenin;Phillygenin, >98%;4-[(3S,3aR,6R,6aR)-6-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol;(+)-Phillygenin;(1S)-1β-(3-Methoxy-4-hydroxyphenyl)-4α-(3,4-dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan;(1S,3aβ,6aβ)-1β-(3-Methoxy-4-hydroxyphenyl)-4α-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan;4-[[(1S)-4α-(3,4-Dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan]-1β-yl]-2-methoxyphenol;Phillygenin | | CAS: | 487-39-8 | | MF: | C21H24O6 | | MW: | 372.41 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products | | Mol File: | 487-39-8.mol |  |
| | (+)-SYLVATESMIN Chemical Properties |
| Melting point | 133℃ | | Boiling point | 534.9±50.0 °C(Predicted) | | density | 1.225 | | storage temp. | 2-8°C(protect from light) | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml | | pka | 9.84±0.35(Predicted) | | form | A crystalline solid | | LogP | 2.034 (est) |
| | (+)-SYLVATESMIN Usage And Synthesis |
| Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Forsythia. | | Uses | (+)-Sylvatesmin is a useful research chemical compound found ias a lignan of forysthia intermedia. | | Biological Activity | Phillygenin is an active component of Forsythia, which has many medicinal values, such as antioxidants, lowering blood lipids, and inhibiting low-density lipoprotein oxidation. | | in vitro | 1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine.
2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay. < /p> | | in vivo | The reference for rat is 5.6 mg/ml ( iv). |
| | (+)-SYLVATESMIN Preparation Products And Raw materials |
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