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| | (-)-Arctigenin Basic information |
| Product Name: | (-)-Arctigenin | | Synonyms: | (3R,4R)-4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-2(3H)-FURANONE;2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R);2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL];ARCTIGENIN:2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R);2(3H)-Furanone,4-[(3,4-dimethoxyphenyl) methyl];dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-,(3R,4R)-;(-)-ARCTIGENIN;ARCTIGENIN | | CAS: | 7770-78-7 | | MF: | C21H24O6 | | MW: | 372.41 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Miscellaneous Natural Products;Protein Kinase | | Mol File: | 7770-78-7.mol |  |
| | (-)-Arctigenin Chemical Properties |
| Melting point | 98.0 to 102.0 °C | | Boiling point | 567.0±45.0 °C(Predicted) | | density | 1.227±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO: 34 mg/mL with heating and sonicating, soluble | | form | solid | | pka | 10.03±0.20(Predicted) | | color | White to Light yellow | | λmax | 280nm(EtOH)(lit.) | | InChIKey | NQWVSMVXKMHKTF-JKSUJKDBSA-N | | LogP | 2.470 (est) | | CAS DataBase Reference | 7770-78-7(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | LY9247000 | | HS Code | 2932.20.4500 |
| | (-)-Arctigenin Usage And Synthesis |
| Uses | Arctigenin is a plant ligan associated with anticancer and antioxidant properties. | | Definition | ChEBI: (-)-Arctigenin is a lignan. | | Biological Activity | Antioxidant, anti-inflammatory, antiproliferative and antiviral agent. Inhibits LPS-induced iNOS expression via inhibition of I κ B α phosphorylation and p65 nuclear translocation (IC 50 = 10 nM). Inhibits HIV-1 replication in vitro . Also potently inhibits MKK1 (IC 50 = 0.5 nM) and provides neuroprotection by binding to kainate receptors. | | storage | -20°C (desiccate) |
| | (-)-Arctigenin Preparation Products And Raw materials |
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