|  | |  |  | sphondin Basic information | 
 | Product Name: | sphondin |  | Synonyms: | sphondin;6-Methoxy-2H-furo[2,3-h][1]benzopyran-2-one;6-Methoxy-2H-furo[2,3-h]-1-benzopyran-2-one;2H-Furo(2,3-h)-1-benzopyran-2-one, 6-Methoxy-;Sfondin;6-Methoxy-2H-furo[2,3-h]chromen-2-one |  | CAS: | 483-66-9 |  | MF: | C12H8O4 |  | MW: | 216.19 |  | EINECS: |  |  | Product Categories: |  |  | Mol File: | 483-66-9.mol |  |  | 
|  |  | sphondin Chemical Properties | 
 | Melting point | 189-191 °C |  | Boiling point | 413.0±45.0 °C(Predicted) |  | density | 1.368±0.06 g/cm3(Predicted) |  | storage temp. | 2-8°C | 
|  |  | sphondin Usage And Synthesis | 
 | Chemical Properties | Off-white needle-like crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Oxtail Duhuo. |  | Uses | Sphondin has an Analgesic, anti-inflammatory, anti-allergic, smooth muscle spasmolytic effect. |  | Definition | ChEBI: Sphondin is a furanocoumarin. |  | Biological Activity | Sphondin, isolated from Heracleum laciniatum, has inhibitory effects on IL-1β-induced increases in COX-2 protein and PGE2 release levels in A549 cells. |  | in vitro |   Pretreatment of A549 cells with Sphondin (10-50 μM) concentration-dependently attenuates IL-1β-induced COX-2 protein expression and PGE  2  release.      |  | target |  | 
|  |  | sphondin Preparation Products And Raw materials | 
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