ChemicalBook Product Catalog Chemical Reagents Organic reagents Esters Ethyl compound (+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE

(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE

(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE Basic information
Product Name:(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE
Synonyms:(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE;Tetra Chloro-Ethyl chloroformate;(±)-1,2,2,2-Tetrachloroethyl chloroformate,98%;(#1)-1,2,2,2-Tetrachloroethyl chloroformate;Carbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester;Paclitaxel Impurity 90
CAS:98015-53-3
MF:C3HCl5O2
MW:246.3
EINECS:
Product Categories:
Mol File:98015-53-3.mol
(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE Structure
(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE Chemical Properties
Boiling point 78 °C15 mm Hg(lit.)
density 1.61 g/mL at 25 °C(lit.)
refractive index n20/D 1.482(lit.)
Fp 193 °F
storage temp. Refrigerator (+4°C)
Safety Information
Hazard Codes T
Risk Statements 23/24/25-34
Safety Statements 26-27-36/37/39-45
RIDADR UN 3390 6.1/PG 1
WGK Germany 3
HazardClass 6.1(a)
PackingGroup II
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE Usage And Synthesis
Chemical PropertiesCLEAR COLOURLESS LIQUID
UsesCarbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester is used in the synthesis of Doxorubicin (D558000), is used as an antineoplastic. Also used in the synthesis of metabolites of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic.
(+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE Preparation Products And Raw materials
4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole BOC-3-ENDO-AMINOBICYCLO[2.2.1]HEPTANE-2-ENDO-CARBOXYLIC ACID (αR,βS)-β-[[(1,1-DiMethylethoxy)carbonyl]aMino]-α-hydroxy-4-(phenylMethoxy)-benzenepropanoic Acid Ethyl Ester 2'-O-tert-Butyl(diMethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel Epothilone B 6-CHLORO-4-CHLOROMETHYL-7-HYDROXY-CHROMEN-2-ONE (4S,5R)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylic acid 2'-O-(Benzyloxycarbonyl) Taxol N-Desbenzoyl-N-tert-butoxycarbonyl-N,O-isopropylidene-3a€-p-O-benzyl-6,7-dehydro Paclitaxel Paclitaxel Impurity 9 7-Xylosyl-10-deacetyltaxol (4S,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid 2'-O-(tert-Butyldimethylsilyl)-6a-hydroxy-7-epi-paclitaxel Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,9-diyl ester, (αR,α'R,βS,β'S)- (9CI) Docetaxel 2’-tert-Butylsimethylsilyl Ether 1,1,2-TRICHLOROETHANE (1,2,2-D3) (+/-)-1,2,2,2-TETRACHLOROETHYL CHLOROFORMATE 2-Chloromethoxyethylchloride
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