Methyl cyclopropane carboxylate

Methyl cyclopropane carboxylate Basic information

Product Name:	Methyl cyclopropane carboxylate
Synonyms:	RARECHEM AL BF 0553;Methyl cyclopropylcarboxylate;lMethyl cyclopropane carboxylate;Methylcyclopropancarboxylat;MEHTYLCYCLOPROPANECARBOXYLATE;methylcyclopropylcarboxylate;METHYL CYCLOPROPANECARBOXYLATE, 99+%;Cyclopropane-1-carboxylic acid methyl ester
CAS:	2868-37-3
MF:	C5H8O2
MW:	100.12
EINECS:	220-690-9
Product Categories:	Cyclopropanes;Simple 3-Membered Ring Compounds;Pharmaceutical Intermediates;Fine Chemical
Mol File:	2868-37-3.mol

Methyl cyclopropane carboxylate Chemical Properties

Boiling point	119 °C/764 mmHg (lit.)
density	0.985 g/mL at 25 °C (lit.)
refractive index	n20/D 1.419(lit.)
Fp	64 °F
storage temp.	Store below +30°C.
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Liquid
color	Clear colorless
Specific Gravity	0.980.985
Water Solubility	Not miscible or difficult to mix in water.
BRN	2039388
InChIKey	PKAHQJNJPDVTDP-UHFFFAOYSA-N
CAS DataBase Reference	2868-37-3(CAS DataBase Reference)
NIST Chemistry Reference	Cyclopropanecarboxylic acid, methyl ester(2868-37-3)
EPA Substance Registry System	Cyclopropanecarboxylic acid, methyl ester (2868-37-3)

Safety Information

MSDS Information

Provider	Language
Methyl cyclopropane carboxylate	English
SigmaAldrich	English
ACROS	English
ALFA	English

Methyl cyclopropane carboxylate Usage And Synthesis

Chemical Properties	CLEAR COLOURLESS LIQUID
Uses	Methyl cyclopropane carboxylate is used as a reagent in the synthesis of N’thiazole and N-pyrazole based inhibitors of MAP kinase p38α.
Uses	It is primarily used an intermediate in the manufacture of pharmaceutical and agrochemical products. Methyl cyclopropane carboxylate is used as a reagent in the synthesis of N?-thiazole and N-pyrazole based inhibitors of MAP kinase p38α.
Definition	ChEBI: Methyl cyclopropanecarboxylate is a methyl ester derived from cyclopropanecarboxylic acid. It is a methyl ester and a member of cyclopropanes. It is functionally related to a cyclopropanecarboxylic acid.
Synthesis Reference(s)	Tetrahedron Letters, 9, p. 4545, 1968 DOI: 10.1016/S0040-4039(01)99181-6

Methyl cyclopropane carboxylate Preparation Products And Raw materials

Raw materials	dimethyl 5,5-dimethylpyrazole-3,4-dicarboxylate-->Methyl 4-bromobutyrate-->Methyl 4-chlorobutyrate-->Methanol-->Cyclopropanecarboxylic acid-->Dibromomethane-->Methyl acetate-->Propargyl alcohol-->1,1-Cyclopropanedicarboxylic acid-->Sodium Methoxide
Preparation Products	5-CYCLOPROPYL-2H-PYRAZOL-3-YLAMINE-->Cyclopropyl 2-fluorobenzyl ketone

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