N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE

N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE Basic information

Product Name:	N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE
Synonyms:	N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE;DMT-dG(dmf) amidite;N2-(dimethylamino)methylene-deoxyguanosine Phosphoramidite;(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((E)-(dimethylamino)methyleneamino)-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite;REF DUPL: DMF-dG-CE-Phophoramidite;N4-(Dimethylamino) methylene)-5'-O-(dimethoxytrityl)-2'-deoxyguanosine-3'-N,N-diisopropyl(cyanoethyl) phosphoramidite;2'-Deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite;DMF-dG-CE Phosphoramidite
CAS:	330628-04-1
MF:	C43H53N8O7P
MW:	824.9
EINECS:	2017-001-1
Product Categories:	DNA Amidites;Fast Deprotection DNA Amidites;Sigma-Proligo;Pharmaceutical;RNAi
Mol File:	330628-04-1.mol

N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE Chemical Properties

Boiling point	876.3±75.0 °C(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO : 100 mg/mL (121.23 mM; Need ultrasonic)
pka	3.80±0.20(Predicted)
form	powder
color	white to off-white
InChIKey	YRQAXTCBMPFGAN-UNHDIWNRSA-N
SMILES	C12N=C(/N=C/N(C)C)NC(=O)C=1N=CN2[C@H]1C[C@@H]([C@@H](COC(C2C=CC=CC=2)(C2C=CC(OC)=CC=2)C2=CC=C(C=C2)OC)O1)OP(OCCC#N)N(C(C)C)C(C)C \|&1:15,17,18,r\|

Safety Information

Safety Statements	24/25
WGK Germany	3
HS Code	29349990

MSDS Information

N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE Usage And Synthesis

Chemical Properties	White or off-white power
Uses	Dmf-dG-CE phosphoramidite is a nucleotide and guanosine (G837895) derivative used in the preparation of synthetic RNA fragments, and other macromolecules such as micellar thrombin-binding aptamers as anticoagulants.

N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE Preparation Products And Raw materials

Raw materials

2'-Deoxyguanosine-->2'-DEOXY-N2-DIMETHYLAMINOMETHYLENE-GUANOSINE-->4,4'-Dimethoxytrityl chloride-->5'-O-(4,4'-Dimethoxytrityl)-N2-dimethylformamidine-2'-deoxyguanosine-->2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite

2',3'-O-Isopropylideneadenosine DMT-2′O-TBDMS-rC(ac) Phosphoramidite 3'-TBDMS-ibu-rG Phosphoramidite N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 6-Chloro-9-beta-D-(2,3-isopropylidene)ribofuranosylpurine 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite DMT-dG(ib) Phosphoramidite 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite 5'-Dimethoxytrityl-3'-deoxythymidine 2'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite 2'-Deoxyguanosine monohydrate AMINO-MODIFIER-C 6-DG CEP 8-BROMO-5'-O-(4,4'-DIMETHOXYTRITYL)-N2-DIMETHYLAMINOMETHYLENE-2'-DEOXYGUANOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE 8-METHOXY-DG CEP 8-ALLYLOXY-3'-O-[(DIISOPROPYLAMINO)(2-CYANOETHOXY)PHOSPHINO]-5'-O-(4,4'-DIMETHOXYTRITYL)-N2-[(DIMETHYLAMINO)METHYLIDINE]-2'-DEOXYGUANOSINE N1-METHYL-DG CEP 8-AMINO-DG CEP α-2'-Deoxyguanosine

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N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE

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