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| | Quercetin dihydrate Basic information |
| Product Name: | Quercetin dihydrate | | Synonyms: | QUERCETIN DIHYDRATE;3,5,7,3',4'-PENTAHYDROXYFLAVONE DIHYDRATE;3,3’,4’,5,7-pentahydroxy-flavondihydrate;Flavone,3,3’,4’,5,7-pentahydroxy-,dihydrate;2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE DIHYDRATE;3,3',4',5,7-PENTAHYDROXYFLAVONE 2H2O;3,3',4',5,7-PENTAHYDROXYFLAVONE DIHYDRATE;3,3',4',5,7-PENTAHYDROXYFLAVONE HYDRATE | | CAS: | 6151-25-3 | | MF: | C15H14O9 | | MW: | 338.27 | | EINECS: | 612-158-3 | | Product Categories: | Flavanols;Biochemistry;Flavonoids;C15 to C38;Carbonyl Compounds;Ketones;Signalling;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Tyrosine Kinase Inhibitors;Inhibitors;TROXEPURE | | Mol File: | 6151-25-3.mol |  |
| | Quercetin dihydrate Chemical Properties |
| Melting point | >300 °C(lit.) | | density | 1.680 g/cm3 | | storage temp. | -20°C | | solubility | Soluble in DMSO > 10 mM | | form | Yellow solid | | Colour Index | 75670 | | color | Yellow | | Water Solubility | practically insoluble | | Merck | 14,8034 | | BRN | 317313 | | InChIKey | GMGIWEZSKCNYSW-UHFFFAOYSA-N | | LogP | 2.075 (est) | | CAS DataBase Reference | 6151-25-3(CAS DataBase Reference) |
| Hazard Codes | T | | Risk Statements | 25-46-23/24/25 | | Safety Statements | 45-53 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | RTECS | LK8950000 | | TSCA | Yes | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29329990 | | Toxicity | LD50 orally in mice: 160 mg/kg (Sullivan) |
| | Quercetin dihydrate Usage And Synthesis |
| Chemical Properties | yellow crystalline powder | | Uses | capillary protectant, antioxidant. antineoplastic, anti-HIV | | Uses | bioflavenoid, antioxidant, antiviral, antimicrobial, enzyme inhibitor | | Uses | Quercetin dihydrate used as a Inhibitor of protein tyrosine kinase, mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. | | General Description | Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate. | | Biochem/physiol Actions | Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. | | target | HMG-CoA Reductase | SOD | Antifection | | storage | Room temperature | | Purification Methods | Crystallise the flavone from aqueous EtOH and dry at 100o. It also sublimes in a vacuum. IR: 2.5 and 16.7 (KBr). max It complexes with Cu2+, Al3+, Ca2+, Ge4+, Zn2+, Ti4+, Zr4+, Th4+, UO4+ . [Beilstein 18 H 242, 18 I 242, 18 II 236, 18 III/IV 3470, 18/5 V 494.] |
| | Quercetin dihydrate Preparation Products And Raw materials |
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