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| | 4-Methoxybenzylchloride Basic information |
| | 4-Methoxybenzylchloride Chemical Properties |
| Melting point | −1 °C(lit.) | | Boiling point | 117-118 °C14 mm Hg(lit.) | | density | 1.155 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.548(lit.) | | Fp | 229 °F | | storage temp. | Inert atmosphere,2-8°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Liquid | | color | Clear colorless to pale yellow | | Water Solubility | slowly decomposes | | Stability: | Moisture Sensitive | | InChIKey | MOHYOXXOKFQHDC-UHFFFAOYSA-N | | CAS DataBase Reference | 824-94-2(CAS DataBase Reference) | | NIST Chemistry Reference | «alpha»-Chloro-4-methoxytoluene(824-94-2) |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-27-36/37/39-45 | | RIDADR | UN 3265 8/PG 3 | | WGK Germany | 3 | | F | 10-19-21 | | Autoignition Temperature | 109℃ | | Hazard Note | Corrosive | | TSCA | No | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29093090 |
| | 4-Methoxybenzylchloride Usage And Synthesis |
| Chemical Properties | Colorless liquid | | Uses | O/N protecting group reagent which can be mildly oxidatively cleaved, e.g., with ceric ammonium nitrate. | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 20, p. 190, 1977 DOI: 10.1021/jm00212a002
The Journal of Organic Chemistry, 53, p. 3634, 1988 DOI: 10.1021/jo00250a048 | | General Description | 4-Methoxybenzyl chloride undergoes mild oxidative claevage with ceric ammonium nitrate. | | Purification Methods | Purify 4-anisyl chloride by fractional distillation under vacuum, and the middle fraction is redistilled at 10-6 mm at room temperature by intermittent cooling of the receiver in liquid N2, and the middle fraction is collected. [Mohammed & Kosower J Am Chem Soc 93 2709 1971, Beilstein 6 IV 2137.] |
| | 4-Methoxybenzylchloride Preparation Products And Raw materials |
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