ChemicalBook Product Catalog Pharmaceutical intermediates Bulk Drug Intermediates ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Basic information
Product Name:((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
Synonyms:3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-ribono-γ-latone;SFBM;(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid γ-lactone 3,5-dibenzoate;Sofosbuvir intermediate;Sofosbuvir Impurity 30;3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-ribono-1,4-lactone;(2R,3R,4R)-2-[(benzoyloxy)methyl]-4-fluoro-4-methyl-5-oxooxolan-3-yl benzoate;Sofosbuvir Intermediate 1
CAS:874638-80-9
MF:C20H17FO6
MW:372.35
EINECS:618-021-4
Product Categories:apis;Sofosbuvir intermediate
Mol File:874638-80-9.mol
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Structure
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Chemical Properties
Melting point 133℃
Boiling point 458.6±34.0 °C(Predicted)
density 1.33
storage temp. 2-8°C
Safety Information
MSDS Information
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Usage And Synthesis
Usesneuromuscular blocking agent
Uses(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic Acid γ-Lactone 3,5-Dibenzoate is a reactant used in the synthesis of 1''-C-cyano-2''-fluoro-2''-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Preparation Products And Raw materials
Raw materialsD-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester-->(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one-->Benzoyl chloride
Sofosbuvir D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester SofosBuvir Impurity 55 D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) SofosBuvir Impurity 40 Sofosbuvir Impurity 17 Sofosbuvir impurity E Sofosbuvir Impurity U PSI-6130 derivative 2'-deoxy-2'-fluoro-2'-C-methyluridine (2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate SofosBuvir Impurity 54 L-Alanine isopropyl ester hydrochloride N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester (3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester sofosBuvir impurity 36
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