Aminopyrazine

Aminopyrazine Basic information

Product Name:	Aminopyrazine
Synonyms:	2-Pyrazinylamine;AMinopyrazine, 99+% 10GR;2-AMINOPYRAZINE FOR SYNTHESIS;Pyrazin-2-amine, 2-Amino-1,4-diazine;APZ;TIMTEC-BB SBB004388;NSC 13147;PYRAZIN-2-AMINE
CAS:	5049-61-6
MF:	C4H5N3
MW:	95.1
EINECS:	225-748-7
Product Categories:	pharmacetical;Pyrazine;Fluorobenzene;API intermediates;Pyrazines;Chloropyrazines, etc.;bc0001
Mol File:	5049-61-6.mol

Aminopyrazine Chemical Properties

Melting point	118-120 °C (lit.)
Boiling point	167.6°C (rough estimate)
density	1.1031 (rough estimate)
refractive index	1.5200 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	soluble in Methanol
pka	3.22±0.10(Predicted)
form	Crystalline Powder
color	Slightly yellow to beige
Water Solubility	soluble
BRN	107025
InChIKey	XFTQRUTUGRCSGO-UHFFFAOYSA-N
LogP	-0.070
CAS DataBase Reference	5049-61-6(CAS DataBase Reference)
NIST Chemistry Reference	Aminopyrazine(5049-61-6)

Safety Information

Hazard Codes	Xi,F
Risk Statements	36/37/38-11
Safety Statements	26-36-37/39
WGK Germany	3
HS Code	29339990

MSDS Information

Provider	Language
2-Aminopyrazine	English
SigmaAldrich	English
ACROS	English
ALFA	English

Aminopyrazine Usage And Synthesis

Chemical Properties	SLIGHTLY YELLOW TO BEIGE CRYSTALLINE POWDER
Uses	2-Aminopyrazine acts as a raw material in a four-component synthesis of imidazolidines. It is also used as an intermediate in synthetic chemistry. In addition, 2-aminopyrazine can be reacted with α-ketohydroximoyl chlorides to form 3-nitrosoimidazo[1,2-a]pyrazines.
Application	2-Aminopyrazine is a synthetic intermediate useful for pharmaceutical synthesis. It is used to synthesize favipiravir and substrate in a four-component synthesis of imidazolidines.
Definition	ChEBI: Aminopyrazine is a member of pyrazines.

Aminopyrazine Preparation Products And Raw materials

Raw materials	2-Amino-3,5-dibromopyrazine-->BenzeneacetaMide, N-cyclohexyl-α-oxo- GlyoxylaMide, N-cyclohexyl-2-phenyl- (6CI,7CI,8CI)-->Pyrazinemethanol, alpha-methyl- (9CI)-->Pyrazinecarbonitrile-->Lumazine-->2-FLUOROPYRAZINE 98-->Iodopyrazine-->Pyrazinamine, N-pyrazinyl--->1H-Isoindol-1-one, 3-hydroxy--->3-Aminopyrazine-2-carboxylic acid-->Pyrazinamide-->Pyrazine-->2-Chloropyrazine
Preparation Products	METHYL 5-BROMOPYRAZINE-2-CARBOXYLATE-->2-Amino-5-bromopyrazine-->2-Amino-3-chloropyrazine-->2-Amino-5-chloropyrazine

Lumazine 2-AMINO-4-HYDROXYPTERIDINE-6-CARBOXYLIC ACID Triamterene Methyl 3-amino-2-pyrazinecarboxylate Pyrazine Aminopyrazine 6-CHLORO-3,5-DIAMINO-2-PYRAZINECARBOXAMIDE benzyl 3-aminopyrazinecarboxylate 3-Aminopyrazine-2-carboxylic acid 3-AMINO-6-(CHLOROMETHYL)-2-PYRAZINECARBONITRILE 4-OXIDE 1-(2-PYRAZINYL)-PIPERAZINE Pyrazinamide 1-Benzylpiperazine 3-METHOXYBENZHYDRAZIDE Sulfachoropyrazine sodium Actinomycin D Glipizide ALLOXAZINE

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