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| | 2-Aminopurine Basic information |
| | 2-Aminopurine Chemical Properties |
| Melting point | 280-282 °C (lit.) | | Boiling point | 238.81°C (rough estimate) | | density | 1.3795 (rough estimate) | | refractive index | 1.7000 (estimate) | | storage temp. | 2-8°C | | solubility | Aqueous Acid (Slightly), Methanol (Slightly, Heated) | | form | Amorphous Powder | | pka | 8.02±0.20(Predicted) | | color | Light beige | | Stability: | Hygroscopic | | InChIKey | MWBWWFOAEOYUST-UHFFFAOYSA-N | | CAS DataBase Reference | 452-06-2(CAS DataBase Reference) | | NIST Chemistry Reference | Purine, 2-amino-(452-06-2) |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38-20/21/22 | | Safety Statements | 22-36-26 | | WGK Germany | 3 | | RTECS | UO7475000 | | HS Code | 29349990 | | Toxicity | mmo-sat 100 mg/PLATE MUREAV 111,283,83 |
| | 2-Aminopurine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | A probe of structural dynamics and charge transfer in DNA . | | Uses | 2-Aminopurine has been used to inhibit eukaryotic initiation factor-2α (eIF2α)-phosphorylation of osteoarthritis (OA) chondrocytes. | | Uses | A probe of structural dynamicas and charge transfer in DNA | | Definition | ChEBI: The parent compound of the 2-aminopurines, comprising a purine core carrying an amino substituent at the 2-position. | | Biochem/physiol Actions | 2-Aminopurine (2AP) is an analog of guanosine and adenosine, which can base pair with cytosine and thymine. It is used as a fluorescent probe in nucleic acid structure and dynamics. 2-Aminopurine (2-AP) inhibits double-stranded RNA-dependent protein kinase, protein kinase R (PKR). | | Safety Profile | Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx. |
| | 2-Aminopurine Preparation Products And Raw materials |
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