ChemicalBook Product Catalog Chemical Reagents Silane reagent (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE Basic information
Product Name:(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE
Synonyms:3-BROMOPROPOXY-T-BUTYLDIMETHYLSILANE;(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE;93-Bromopropoxy)-tert-butyldimethylsilane(Na2CO3 stabiliszer)975;Silane,(3-bromopropoxy)(1,1-dimethylethyl)dimethyl-;3-BroMoethoxy-tert-butyl diMethylsilane;(3-BroMopropoxy)-tert-butyldiMethylsilane, 97%, stabilized over sodiuM carbonate;(3-BroMopropoxy)-t-buyl-1-diMethylsilane;(3-Bromopropoxy)-tert-butyldimethylsilane 97%
CAS:89031-84-5
MF:C9H21BrOSi
MW:253.25
EINECS:
Product Categories:Building Blocks;Chemical Synthesis;Protected Alcohols/Phenols;Organic Building Blocks;Oxygen Compounds;Protected Alcohols/Phenols;Organic Building Blocks;Oxygen Compounds
Mol File:89031-84-5.mol
(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE Structure
(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE Chemical Properties
Boiling point 182 °C(lit.)
density 1.093 g/mL at 25 °C(lit.)
refractive index n20/D 1.451(lit.)
Fp 185 °F
storage temp. 2-8°C
solubility Chloroform (Sparingly)
form Oil
color Colourless
InChIKeyQGMROEZDWJTIDW-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
TSCA No
HS Code 29319090
MSDS Information
ProviderLanguage
SigmaAldrich English
(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE Usage And Synthesis
UsesThe propanol functionality of this versatile reagent can be introduced to many pharmaceuticals.1,2,3,4
Uses(3-Bromopropoxy)-tert-butyldimethylsilane may be used to introduce propanol functionality to many pharmaceuticals.
It may be used as an alkylating agent in the synthesis of the following:
  • N-[2-[N-[3-(tert-butyldimethylsilyloxy)propyl]-N-ethylamino]ethyl]phthalimide
  • O-(3-tert-butyldimethylsilyloxypropyl)-N-(tert-butoxycarbonyl)-L-tyrosine methyl ester
  • tert-butyldimethyl-[3-(3-methyl-2-nitrophenoxy)propoxy]silane
Uses(3-Bromopropoxy)-tert-butyldimethylsilane is a reagent in the preparation of piperidinylcarbonyl sulfamates as a novel class of antihyperlipidemic agents with LDL-receptor up-regulation via the adaptor protein autosomal recessive hypercholesterolemia.
General Description(3-Bromopropoxy)-tert-butyldimethylsilane is a bromo silyl ether.
T-BUTYLDIMETHYLSILANE (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE TRANS-3-BROMO-5-TERT-BUTYL-DIMETHYLSILYLOXY-2-PENTEN-1-OL
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