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| | 15-Methoxypinusolidic acid Basic information |
| Product Name: | 15-Methoxypinusolidic acid | | Synonyms: | 15-Methoxypinusolidic acid;(1S,4~{a}R,5S,8~{a}R)-5-[2-(2-methoxy-5-oxo-2~{H}-furan-4-yl)ethyl]-1,4~{a}-dimethyl-6-methylidene-3,4,5,7,8,8~{a}-hexahydro-2~{H}-naphthalene-1-carboxylic acid;15-methoxyconiferous acid;1-Naphthalenecarboxylic acid, 5-[2-(2,5-dihydro-5-methoxy-2-oxo-3-furanyl)ethyl]decahydro-1,4a-dimethyl-6-methylene-, (1S,4aR,5S,8aR)- | | CAS: | 769928-72-5 | | MF: | C21H30O5 | | MW: | 362.46 | | EINECS: | | | Product Categories: | | | Mol File: | 769928-72-5.mol |  |
| | 15-Methoxypinusolidic acid Chemical Properties |
| Boiling point | 531.4±50.0 °C(Predicted) | | density | 1.16±0.1 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 4.67±0.60(Predicted) |
| | 15-Methoxypinusolidic acid Usage And Synthesis |
| Description | 15-Methoxypinusolidic acid induced apoptosis in murine microglial cells, presumably via inhibition of the cell cycle progression.
15-Methoxypinusolidic acid inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB, suggesting a potential anti-inflammatory effect of the compound on microglial cells.
3. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dependent adipogenic gene expression.
4. 15-Methoxypinusolidic acid attenuates glutamate-induced excitotoxicity via stabilization of [Ca2+]i homeostasis and suppression of oxidative stress possibly through the actions on the NMDA receptors. | | target | NOS | NO | PPAR | Calcium Channel | NF-kB | NMDAR | p38MAPK | ERK | JNK | IL Receptor | COX |
| | 15-Methoxypinusolidic acid Preparation Products And Raw materials |
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