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| | Benzyltriethylammonium chloride Basic information |
| | Benzyltriethylammonium chloride Chemical Properties |
| Melting point | 190-192 °C (dec.) (lit.) | | Boiling point | 366.11°C (rough estimate) | | density | 1.08 g/mL at 25 °C | | refractive index | n20/D 1.479 | | Fp | >100°C | | storage temp. | Store below +30°C. | | solubility | H2O: 0.1 g/mL, clear | | form | Liquid | | color | White to beige | | PH | 6-8 (100g/l, H2O, 20℃) | | PH Range | 6 - 8 | | Water Solubility | 700 g/L (20 ºC) | | Sensitive | Hygroscopic | | Decomposition | 185°C | | BRN | 3574984 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChIKey | HTZCNXWZYVXIMZ-UHFFFAOYSA-M | | CAS DataBase Reference | 56-37-1(CAS DataBase Reference) | | EPA Substance Registry System | Benzyltriethylammonium chloride (56-37-1) |
| | Benzyltriethylammonium chloride Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder. soluble in water, aqueous solutions conduct electricity. It is hydrochloride salt of benzyltriethylammonium which acts as a phase-transfer catalyst in chemical reactions. | | Uses | Benzyltriethylammonium chloride is used as a catalyst in the preparation of 2-phenylbutyronitrile from phenyl acetonitrile. It is involved in the Knoevenagel condensation of carbonyl compounds with active methylene compounds to give olefinic products. It acts as a phase transfer catalyst used in the alkylation reaction. It reacts with 1H-Pyridine-2-thione to get 2-Benzylsulfanyl-pyridine. | | Application | Benzyltriethylammonium chloride is a lipophilic phase-transfer catalyst that can be used in phase-transfer catalysis (PTC) to catalyze polycondensation reactions to form high molecular weight polymers under bi-phasic conditions.
It can also be used:
To activate hydroxyapatite and natural phosphate for use as a solid support for Knoevenagel condensation and Claisen-Schmidt condensation, respectively at room temperature and in the absence of a solvent.
To increase the efficiency of mCPBA oxidation of sulfonimine generated from arenesulfonamide and diethyl acetal of an aromatic aldehyde to form 2-sulfonyloxaziridines.
In combination with antimony(V) chloride to form a catalytic system for the Friedel-Crafts acylation reactions of arenes with acyl and sulfonyl chlorides. | | Preparation | Benzyltriethylammonium chloride synthesis: Add benzyl chloride, triethylamine and acetone into the reaction pot, and reflux at 63-64°C for 8 hours. Slowly lowered to 15°C, filtered, and the filter cake was washed with acetone and dried to obtain benzyltriethylammonium chloride. Yield 68.9%. | | Safety Profile | Poison by intravenous route.When heated to decomposition it emits toxic vapors ofNOx and Cl. |
| | Benzyltriethylammonium chloride Preparation Products And Raw materials |
| Raw materials | Triethylamine-->Acetone-->Benzyl chloride | | Preparation Products | 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE-->4-BROMOMETHYLTETRAHYDROPYRAN-->2,5-Diamino-4,6-dichloropyrimidine-->Chlorpyrifos-->2-Ethoxybenzoic acid-->2-AMINOPENT-4-YNENITRILE-->1-AMINOCYCLOPROPANECARBONITRILE-->6-BROMO-2H-1,4-BENZOXAZIN-3(4H)-ONE-->6,6'-Dimethyl-2,2'-dipyridyl-->2,2-DICHLORO-1-METHYLCYCLOPROPANAMINE-->Cypermethrin-->N-(3-Trifluoromethylphenyl)piperazine-->TERPINEOL-->Chlorpyrifos-methyl-->Diiodomethane-->3-(CYANOMETHYL)-2,4,5-TRIMETHYLTHIOPHENE-->4'-BROMO-3'-METHYLACETANILIDE-->1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone-->Phosazetim-->Chlorphoxim-->1-(2-Methoxyphenyl)piperazine-->TERT-BUTYL ISOCYANIDE-->Disperse Violet 26-->2-Amino-2,3-dimethylbutyronitrile-->(O，O-di-4-chlorophenyl)thiophosphenyl chloride |
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