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Fmoc-L-Serine

Fmoc-L-Serine Basic information
Product Name:Fmoc-L-Serine
Synonyms:Fmoc-L-serine ,99%;N-FMoc-L-serine, 97+%;N-Fmoc-L-serine Fmoc-Ser-OH;L-Serine-d3-N-FMOC;FMoc-Ser-OH (FMoc-L-Serine);(S)-2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)-3-hydroxypropanoic acid;FMoc-Ser.H2O;L-SERINE-N-FMOC (13C3,15N)
CAS:73724-45-5
MF:C18H17NO5
MW:327.33
EINECS:690-938-2
Product Categories:Serine [Ser, S];Fmoc-Amino Acids and Derivatives;Protected Amino Acids;Amino Acids (N-Protected);Biochemistry;Fmoc-Amino Acids;Amino Acids;Fmoc-Amino acid series
Mol File:73724-45-5.mol
Fmoc-L-Serine Structure
Fmoc-L-Serine Chemical Properties
Melting point 104-106°C
alpha -12.5 º (c=1%, DMF)
Boiling point 599.3±50.0 °C(Predicted)
density 1.362±0.06 g/cm3(Predicted)
refractive index -12.5 ° (C=1, DMF)
storage temp. 2-8°C
solubility soluble in Methanol
pka3.51±0.10(Predicted)
form powder to crystal
color White to Light yellow
optical activity[α]20/D 12.5±1°, c = 1% in DMF
BRN 4715791
InChIInChI=1S/C18H17NO5/c20-9-16(17(21)22)19-18(23)24-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16,20H,9-10H2,(H,19,23)(H,21,22)/t16-/m0/s1
InChIKeyJZTKZVJMSCONAK-INIZCTEOSA-N
SMILESC(O)(=O)[C@H](CO)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference73724-45-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-26
WGK Germany 3
HS Code 29242990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Fmoc-L-Serine Usage And Synthesis
Chemical PropertiesLight yellow powder
UsesN-Fmoc-L-serine is an N-Fmoc-protected form of L-Serine (S270975). L-Serine is a nonessential amino acid that is required for the synthesis of sphingolipids and phosphatidylserine, compounds that are important for central nervous system neuronal survival. L-Serine is also important in intermediary metabolism in eukaryotic cells.
Fmoc-L-Serine Preparation Products And Raw materials
Preparation ProductsFmoc-O-(benzylphospho)-L-serine-->MELITTIN-->N-(9-Fluorenylmethoxycarbonyl)-L-serine Phenacyl Ester-->H-SER-PRO-OH
FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH FMOC-SER(BZL)-OH FMOC-THR(TBU)-OPFP Fmoc-Asp(OtBu)-OH FMOC-SER(TBU)-OSU FMOC-SER(TBU)-OPFP FMOC-L-SER(GAL(1->3)GALNAC)-OH Fmoc-O-tert-Butyl-L-serine 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl ester FMOC-L-SERINE (TBU),FMOC-L-SERINE(O-T-BUTYL),O-tert-Butyl-N-Fmoc-L-serine FMOC-O-tert-Butyl-L-threonine FMOC-L-THR(GAL(1->3)GALNAC)-OH Fmoc-O-trityl-L-serine L-Fmoc-Aspartic acid alpha-tert-butyl ester 9-Fluorenylmethyl chloroformate DL-Serine Fmoc-Phe-OH FMOC-SER(AC)-OH N-(9-Fluorenylmethoxycarbonyloxy)succinimide
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