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| | Leonurine hydrochloride Basic information |
| | Leonurine hydrochloride Chemical Properties |
| Melting point | 238 °C | | Boiling point | 496.7±55.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | DMSO: soluble2mg/mL, clear (warmed) | | pka | 8.26±0.25(Predicted) | | form | powder | | color | white to beige | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. | | InChIKey | WNGSUWLDMZFYNZ-UHFFFAOYSA-N |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-24/25 | | WGK Germany | 3 | | HS Code | 29399990 |
| | Leonurine hydrochloride Usage And Synthesis |
| Description | An amorphous alkaloid, leonurine has been obtained from the leaves of Leonurus
sibiricus L. and is characterized as the crystalline hydrochloride hydra te, m.p.
19l-4°C. Hydrolysis yields syringic acid and Q-hydroxybutylguanidine. The
total synthesis of the alkaloid has been achieved, confirming the above structure. | | Uses | Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus. A natural product with antioxidant, anti-inflammatory and cardioprotective properties for the treatment of wild variety of conditions including stroke, cerebral thrombosis and cardiovascular diseases. | | Uses | Leonurine Hydrochloride is an alkaloid plant extract used in the treatment of uterine disorders. Used in the modification of uterine contractions in rats. | | Definition | ChEBI: Leonurine is a trihydroxybenzoic acid. | | References | Kubota, Nakajima., Nippon Yakubusugaku Zasshi., 163 (1930)
Goto et al., Tetrahedron Lett., 545 (1962)
Total synthesis:
Kishi et al., Tetrahedron Lett., 637 (1968) |
| | Leonurine hydrochloride Preparation Products And Raw materials |
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