|  | |  |  | 1,4-Butane sultone Basic information | 
 | Product Name: | 1,4-Butane sultone |  | Synonyms: | 1,4-butylenesulfone;1,4-Butylsultone;1,4-BUTANE SULTONE, 99+%;1,4-Bs1,4-ButaneSultone;2,2-Dioxide-1,2-oxathiane;δ-Valerosultone;1,4-Butane;4-hydroxy-1-butanesulfonic acid sultone |  | CAS: | 1633-83-6 |  | MF: | C4H8O3S |  | MW: | 136.17 |  | EINECS: | 216-647-9 |  | Product Categories: | Building Blocks;Chemical Synthesis;Heterocycles;Heterocyclic Building Blocks;Others;S-Containing |  | Mol File: | 1633-83-6.mol |  |  | 
|  |  | 1,4-Butane sultone Chemical Properties | 
 | Melting point | 12-15 °C (lit.) |  | Boiling point | >165 °C/25 mmHg (lit.) |  | density | 1.331 g/mL at 25 °C (lit.) |  | refractive index | n20/D 1.464(lit.) |  | Fp | >230 °F |  | storage temp. | Store below +30°C. |  | solubility | 54g/l (decomposition) |  | form | Liquid |  | color | Clear colorless to yellow |  | Water Solubility | 54 g/L (20 ºC) decomposes |  | Sensitive | Moisture Sensitive |  | BRN | 110588 |  | InChIKey | MHYFEEDKONKGEB-UHFFFAOYSA-N |  | CAS DataBase Reference | 1633-83-6(CAS DataBase Reference) |  | EPA Substance Registry System | 1,2-Oxathiane, 2,2-dioxide (1633-83-6) | 
|  |  | 1,4-Butane sultone Usage And Synthesis | 
 | Chemical Properties | Butanesultone is a viscous, clear, colourless – or yellowish/brown – and odourless liquid. When heated, vapours of butanesultone are known to form explosive mixtures with air and are reported to cause explosion hazards. |  | Uses | 1,4-Butane Sultone is an alkylating agent with weak carcinogenic activity. |  | Uses | 1,4-Butane sultone can be employed as a reactant in the preparation of conjugated polymers which include polybetaine, poly[2-ethynyl-N-(4-sulfobutyl)pyridinium betaine] (PESPB). It can also be used in the preparation of Bronsted acid catalysts such as 4-(succinimido)-1-butane sulfonic acid and poly(4-vinylpyridinium butane sulfonic acid) hydrogen sulfate. These catalysts facilitate the synthesis of 1-amidoalkyl-2-naphthols, substituted quinolines, and pyrano[4,3-b]pyran derivatives.
 |  | Application | 1,4-Butane sultone is an intermediate widely used for sulfonated surfactants.It is also applied in photo development and electroplating.It is 
used as the Intermediate for the production of APIs.It used in 
sulfobutylether-β-cyclodextrin(SEBCD). |  | Safety Profile | Suspected carcinogen 
with experimental tumorigenic data. Poison 
by subcutaneous, intravenous, and 
intraperitoneal routes. Moderately toxic by 
ingestion. Experimental reproductive 
effects. Human mutation data reported. See 
also SULFONATES. When heated to 
decomposition it emits toxic fumes of SOx |  | Synthesis | Performing sulfonation on 3-butylene-1-alcohol or 3-butylene-1-chlorine serving as a raw material and a sulfonating agent under the oxidation-reduction of an initiator;performing acidification after the reaction is finished;performing lactonization by high vacuum dehydration cyclization and azeotropic dehydration cyclization;and finally refining to obtain a 1,4-butane sultone finished product. | 
|  |  | 1,4-Butane sultone Preparation Products And Raw materials | 
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