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| | Tosufloxacin tosylate Basic information |
| Product Name: | Tosufloxacin tosylate | | Synonyms: | TOSUFLOXACIN TOSYLATE;1,8-naphthyridine-3-carboxylicacid,7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluoro;4-dihydro-4-oxo-phenyl)-6-fluoro-mono(4-methylbenzenesulfonate);a64730;t3262;1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, mono(4-methylbenzenesulfonate) (9CI);Tosuxacin;7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid 4-methylbenzenesulfonate | | CAS: | 115964-29-9 | | MF: | C26H23F3N4O6S | | MW: | 576.55 | | EINECS: | | | Product Categories: | Biochemistry;Quinolones (Antibiotics for Research and Experimental Use);Intermediates & Fine Chemicals;Pharmaceuticals;Antibiotics for Research and Experimental Use | | Mol File: | 115964-29-9.mol |  |
| | Tosufloxacin tosylate Chemical Properties |
| Melting point | 251-252°C | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | neat | | color | White to Pale Yellow | | BRN | 7617816 | | CAS DataBase Reference | 115964-29-9 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | QN2791000 | | HS Code | 29339900 |
| | Tosufloxacin tosylate Usage And Synthesis |
| Description | Tosufloxacin tosylate is a new fluoroquinolone antibacterial structurally related to
temafloxacin. Mechanistically, it is a microbial DNA topoisomerase inhibitor,
useful against beta-lactamase producing organisms. Tosufloxacin tosylate is reported to be particularly effective against Salmonella enteritidis. | | Chemical Properties | White to Off-White Solid | | Originator | Toyama (Japan) | | Uses | Useful as a therapeutic antimicrobial for the treatment of respiratory infections. | | Definition | ChEBI: Tosufloxacin tosylate is a racemate comprising equimolar amounts of (R)- and (S)-tosufloxacin tosylate. It has a role as an antimicrobial agent, an antiinfective agent, a DNA synthesis inhibitor, a hepatotoxic agent and a topoisomerase IV inhibitor. It contains a tosufloxacin(1+), a (S)-tosufloxacin tosylate and a (R)-tosufloxacin tosylate. | | Brand name | Ozex; Tosuxacin |
| | Tosufloxacin tosylate Preparation Products And Raw materials |
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