ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Proline derivatives L(-)-Thiazolidine-4-carboxylic acid

L(-)-Thiazolidine-4-carboxylic acid

L(-)-Thiazolidine-4-carboxylic acid Basic information
Product Name:L(-)-Thiazolidine-4-carboxylic acid
Synonyms:thiazolidinecarboxylicacid;(R)-(-)-THIAZOLIDINE-4-CARBOXYLIC ACID;(R)-THIAZOLIDINE-4-CARBOXYLIC ACID;THIOPROLINE;THIAPROLINE;L-Thiaolidine-4-carboxylic acid;L-THIAPROLINE;L(-)-THIAZOLIDINE-4-CARBOXYLIC ACID
CAS:34592-47-7
MF:C4H7NO2S
MW:133.17
EINECS:252-106-3
Product Categories:Proline [Pro, P];Amino Acids;INTERMEDIATES
Mol File:34592-47-7.mol
L(-)-Thiazolidine-4-carboxylic acid Structure
L(-)-Thiazolidine-4-carboxylic acid Chemical Properties
Melting point 190-200 °C (dec.)(lit.)
alpha -101 º (c=1, 1N HCl)
density 1.226 (estimate)
vapor pressure 0.001Pa at 60℃
refractive index -200 ° (C=1, 1mol/L NaOH)
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly, Heated), Water (Sparingly, Heated, Sonicated)
pKa2.09±0.20(Predicted)
form Flakes
Boiling point 350.3±37.0 °C(Predicted)
color White to light yellow-beige to pink
optical activity[α]20/D 141°, c = 1.3 in H2O
Water Solubility 28.5 g/L (20 ºC)
Merck 14,9445
BRN 81065
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyDZLNHFMRPBPULJ-VKHMYHEASA-N
LogP-241--3.01 at 22℃ and pH4-9
CAS DataBase Reference34592-47-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38-20/21/22
Safety Statements 26-36/37/39-36
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS XJ5425500
HazardClass 6.1(b)
PackingGroup III
HS Code 29341000
MSDS Information
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L(-)-Thiazolidine-4-carboxylic acid English
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ALFA English
L(-)-Thiazolidine-4-carboxylic acid Usage And Synthesis
Chemical Propertiessolid
UsesUsed in peptide coupling reactions.
DefinitionChEBI: An optically active version of thioproline having L-configuration.
L(-)-Thiazolidine-4-carboxylic acid Preparation Products And Raw materials
Preparation ProductsPidotimod-->N-Acetyl-L-thiazolidine-4-carboxylic acid-->methyl (R)-thiazolidine-4-carboxylate hydrochloride-->methyl (R)-thiazolidine-4-carboxylate-->N-Acetyl-L-thioproline
7-(2,2-DIMETHYL-5-OXO-4-PHENYL-IMIDAZOLIDIN-1-YL)-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID L-THIOPROLINE 6-Aminopenicillanic acid Penicillin V potassium salt (S)-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID Ampicillin Amoxicillin LABOTEST-BB LT00440843 (R)-2,2-DIMETHYL 4-THIAZOLIDINECARBOXYLIC ACID HYDROCHLORIDE 2-(2-THIENYL)-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID Dicloxacillin sodium Penicillin G potassium salt 5,5-DIMETHYL-2-PHENYL-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID Cloxacillin-13C4 SodiuM Salt (R)-2,2-DIMETHYL-3-FORMYL 4-THIAZOLIDINECARBOXYLIC ACID Nafcillin sodium salt monohydrate N-Acetyl-L-thiazolidine-4-carboxylic acid Mezlocillin
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