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| | Secoisolariciresinol diglucoside Basic information |
| Product Name: | Secoisolariciresinol diglucoside | | Synonyms: | β-D-Glucopyranoside, (2S,3S)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-;Secoisolariciresinoldiglucoside/(SS)-Secoisolariciresinoldiglucoside;(S,S)-SDG;(S,S)-Secoisolariciresinol diglucoside | | CAS: | 257930-74-8 | | MF: | C32H46O16 | | MW: | 686.7 | | EINECS: | | | Product Categories: | | | Mol File: | 257930-74-8.mol |  |
| | Secoisolariciresinol diglucoside Chemical Properties |
| Boiling point | 989.2±65.0 °C(Predicted) | | density | 1.52±0.1 g/cm3(Predicted) | | pka | 9.80±0.20(Predicted) |
| | Secoisolariciresinol diglucoside Usage And Synthesis |
| Biological Activity | Secoisolariciresinol diglucoside ((S,S)-SDG), the major lignan in whole wheat flaxseed, has anti-inflammatory, antioxidant, anti-mutagenic, antimicrobial, anti-obesity, hypolipidemic and neuroprotective effects. | | in vitro | Secoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals. | | in vivo | Secoisolariciresinol diglucoside (4 mg/mouse; a single po) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation. | Animal Model: < /td> | Hand feeding mice (10 weeks old, male) are injected with TNFα | | Dosage: | 4 mg/mouse | | Administration: | Po 2 h before ic administration of TNFα | | Result: | Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%. | |
| | Secoisolariciresinol diglucoside Preparation Products And Raw materials |
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