ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Ethylpyridine 3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)

3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)

3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone) Basic information
Product Name:3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)
Synonyms:3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone);3-(2-chloroethyl)-2-Methyl-9-hydroxy-4H-pyrido[1,2-a]pyriMidine-4-one;9-Hydroxy-3-(2-chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one;3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one;3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one;Paliperidone-1;Paliperidone impurity 17/3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one;3-(2-chloroethyl)-9-hydroxy-
CAS:260273-82-3
MF:C11H11ClN2O2
MW:238.67
EINECS:
Product Categories:APIs Intermediate
Mol File:260273-82-3.mol
3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone) Structure
3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone) Chemical Properties
Boiling point 413.1±55.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
solubility Dichloromethane; Methanol
form Solid
pka8.05±0.20(Predicted)
color Beige
Safety Information
MSDS Information
3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone) Usage And Synthesis
Uses3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a byproduct in the synthesis of 5-Fluoro Paliperidone (F595170), which is a Paliperidone (P141000) impurity.
3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone) Preparation Products And Raw materials
Preparation Products3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
9-Benxyloxy-3-(2-Chloro ethyl)-2-methyl pyrido[1,2-a]pyrimidine-4-one 3-ethyl-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride 5-Fluoro Paliperidone Paliperidone Impurity 4 RAC 9-HYDROXYRISPERIDONE-D4 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 9-Keto Risperidone Paliperidone E-Oxime 3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one (S)-9-Hydroxy Risperidone 9-hydroxy-2-methyl-3-vinyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one 3-(2-chloroethyl)-9-oxo-2-methyl-6,7,8,9-tetrahydro-4H-pyrido-[1,2-a]pyrimidin-4-one Paliperidone 3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone) 3-(2-CHLOROETHYL-D4)-2-METHYL-9-(PHENYLMETHOXY)-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE 3-(2-Chloroethyl)-2-methylpyrido[1,2-a]pyrimidin-4-one 3-(2-chloroethyl)-4H-pyrido[1,2-a]pyrimidin-4-one
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