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| | alpha-Azido-omega-hydroxy octa(ethylene glycol) Basic information |
| Product Name: | alpha-Azido-omega-hydroxy octa(ethylene glycol) | | Synonyms: | Azido-PEG (n=7);O-(2-Azidoethyl)heptaethylene glycol;3,6,9,12,15,18,21-heptaoxatricosan-1-ol,23-azide;23-Azido-3,6,9,12,15,18,21-Heptaoxatricosan-1-ol;O-(2-Azidoethyl)heptaethylene glycol >=95% (oligomer purity);Azido-PEG8-alcohol;Azide-PEG8-Alcohol;Azido-PEG7-alcohol | | CAS: | 352439-36-2 | | MF: | C16H33N3O8 | | MW: | 395.45 | | EINECS: | | | Product Categories: | Aliphatic Azides;Alkynes and Other Reagents;Azides;Building Blocks;Chemical Biology;Chemical Synthesis;Heterobifunctional PEG;Conjugation Chemistry: Azides;Nitrogen Compounds;Organic Building Blocks;PEG Azides;PEGylation;peg | | Mol File: | 352439-36-2.mol |  |
| | alpha-Azido-omega-hydroxy octa(ethylene glycol) Chemical Properties |
| storage temp. | 2-8°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | BRN | 8940056 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | HS Code | 2929900090 |
| | alpha-Azido-omega-hydroxy octa(ethylene glycol) Usage And Synthesis |
| Description | Azide-PEG8-alcohol is a click chemistry reagent with an azide(N3) and a terminal hydroxyl group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl (OH) group enables further derivatization or replacement with other functional groups. | | Uses | O-(2-Azidoethyl)heptaethylene glycol is used to synthesize oligo and poly(ethylene glycol) derivatives that are used as structural units of dendrimers, hydrogels, surface modifiers, self-assembling systems and molecular crosslinkers. This precursor is compatible for acetylene-azide click reactions.
Some of the reported applications include:
- Synthesis of strain-stiffening hydrogels through self-assembly of oligomers fibres derived from Azido-PEG (n=7).
- Synthesis of biodegradable tetra-PEG hydrogels for drug delivery system.
- Synthesis of heterobifunctional oligo(ethylene glycol) linkers for bioconjugation and targeted drug delivery.
- Preparation of synthetic amphiphiles for programmed pH-dependent dispersions of carbon nanotubes (CNTs).
- Selective glycoprotein detection through allosteric click-imprinting by using a self-assembled monolayer developed from the above oligomer.
- Preparation of bioactivated quantum dot micelles containing fluorescent nanocrystals.
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| | alpha-Azido-omega-hydroxy octa(ethylene glycol) Preparation Products And Raw materials |
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