|
| | Tilorone dihydrochloride Basic information |
| | Tilorone dihydrochloride Chemical Properties |
| Melting point | 230-233 °C(lit.) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Methanol (Slightly) | | form | Solid | | color | Orange | | Merck | 14,9440 | | InChIKey | BSVYJQAWONIOOU-UHFFFAOYSA-N | | CAS DataBase Reference | 27591-69-1(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 20/21/22-36/37/38-40 | | Safety Statements | 7-22-26-37/39 | | WGK Germany | 3 | | RTECS | LL9000000 | | HS Code | 2922.39.4500 | | Toxicity | LD50 in mice, rats (single dose): 959, 852 mg/kg orally; 145, 244 mg/kg i.p. (Krueger, Mayer) |
| | Tilorone dihydrochloride Usage And Synthesis |
| Description | Tilorone is an orally active, antiviral compound that induces interferon production and is reported to have antitumor, anti-inflammatory, and neuroprotective actions. With chronic administration, tilorone induces lysosomal glycosaminoglycan storage, rendering glycosaminoglycans resistant to enzymatic degradation. | | Chemical Properties | Orange-yellow crystalline powder | | Uses | Tilorone dihydrochloride was used to study the interaction of drugs with synthetic self-complementary DNA by SPR (Surface Plasmon Resonance). | | Uses | Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent. | | Definition | ChEBI: Tilorone dihydrochloride is the dihydrochloride salt of tilorone. It is used as an antiviral drug to treat influenza, herpes infection, viral hepatitis, acute respiratory viral infections and SARS. It has a role as an anti-inflammatory agent, an antineoplastic agent, an interferon inducer, a nicotinic acetylcholine receptor agonist and an antiviral drug. It contains a tilorone(2+). | | Brand name | Tilorone is INN. | | General Description | Effect of tilorone dihydrochloride on the changes of transmembrane potential of mitochondrial membranes of the isolated rat hepatocytes has been investigated. Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent. |
| | Tilorone dihydrochloride Preparation Products And Raw materials |
|
