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| | (IODOMETHYL)TRIMETHYLSILANE Basic information |
| | (IODOMETHYL)TRIMETHYLSILANE Chemical Properties |
| Melting point | 137-141 °C | | Boiling point | 139-141 °C (lit.) | | density | 1.443 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.491(lit.) | | Fp | 89 °F | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | Difficult to mix. | | form | clear liquid | | color | Colorless to Light orange to Yellow | | Specific Gravity | 1.441 | | Sensitive | Light Sensitive | | Hydrolytic Sensitivity | 3: reacts with aqueous base | | BRN | 1731485 | | InChIKey | VZNYXGQMDSRJAL-UHFFFAOYSA-N | | CAS DataBase Reference | 4206-67-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 10-36/37/38 | | Safety Statements | 26-36-24/25-16 | | RIDADR | UN 2924 3/PG 3 | | WGK Germany | 3 | | F | 8-10-21 | | TSCA | No | | HazardClass | 3.2 | | PackingGroup | III | | HS Code | 29319090 |
| | (IODOMETHYL)TRIMETHYLSILANE Usage And Synthesis |
| Chemical Properties | CLEAR YELLOW TO BROWN LIQUID | | Physical properties | bp 140–142 °C; d 1.442 g cm?3. | | Uses | (Iodomethyl)trimethylsilane can be used as electrophile for the preparation of allylsilanes and propargylsilanes;
forms carbon alkylation adducts useful for alkene
synthesis; alkylation adducts are frequently a source of fluorideinduced
reactive intermediates, forming nitrogen and sulfur
alkylation adducts that function as ylide precursors; readily undergoes
metal–halogen exchange to generate a reagent for Peterson
methylenation. | | Uses | (Iodomethyl)trimethylsilane is used for the N-alkylation of amides, in a reaction sequence to prepare unstabilized ylides for [2+3]-cycloadditions. It can react with acetoacetic acid ethyl ester to get 3-trimethylsilanyl-proπonic acid ethyl ester. | | Purification Methods | If slightly violet in colour, wash it with aqueous 1% sodium metabisulfite, H2O, dry (Na2SO4) it and fractionally distil it at 760mm. [Whitmore & Sommer J Am Chem Soc 68 481 1946, Beilstein 4 IV 3878.] |
| | (IODOMETHYL)TRIMETHYLSILANE Preparation Products And Raw materials |
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