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| | Dovitinib Dilactic acid (TKI258 Dilactic acid) Basic information |
| Product Name: | Dovitinib Dilactic acid (TKI258 Dilactic acid) | | Synonyms: | Dovitinib Dilactic acid (TKI258 Dilactic acid);2-Hydroxypropanoic acid compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone;Dovitinib dilactic acid;TKI258 Dilactic acid;Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone;Dovitinib dilactic acid, >=99%;Dovitinib (TKI-258) Dilactic Acid;CHIR-258 DILACTIC ACID | | CAS: | 852433-84-2 | | MF: | C24H27FN6O4 | | MW: | 482.52 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 852433-84-2.mol |  |
| | Dovitinib Dilactic acid (TKI258 Dilactic acid) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO > 10 mM | | form | Powder |
| | Dovitinib Dilactic acid (TKI258 Dilactic acid) Usage And Synthesis |
| Uses | Dovitinib Dilactic acid is the Dilactic acid of Dovitinib (D537000, Lactate salt), which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit), also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Potent FGFR inhibitor | | Uses | Dovitinib (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively. |
| | Dovitinib Dilactic acid (TKI258 Dilactic acid) Preparation Products And Raw materials |
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