1-Fluoro-4-iodobenzene

1-Fluoro-4-iodobenzene Basic information

Product Name:	1-Fluoro-4-iodobenzene
Synonyms:	4-FLUORO-1-IODOBENZENE;4-FLUOROIODOBENZENE;P-FLUOROIODOBENZENE;1-FLUORO-4-IODOBENZENE;1-Fluoro-4-iodobenzene, 97+%;Fluorine iodobenzene;1-FL;uoro-4-iodobenzene
CAS:	352-34-1
MF:	C6H4FI
MW:	222
EINECS:	206-522-7
Product Categories:	Aromatic Hydrocarbons (substituted) & Derivatives;Fluorobenzene;Miscellaneous;Fluorine Compounds;Iodine Compounds;Aryl;C6;Halogenated Hydrocarbons;alkyl Iodine\| alkyl Fluorine;Pyridines ,Halogenated Heterocycles
Mol File:	352-34-1.mol

1-Fluoro-4-iodobenzene Chemical Properties

Melting point	-20 °C (lit.)
Boiling point	182-184 °C (lit.)
density	1.925 g/mL at 25 °C (lit.)
refractive index	n20/D 1.583(lit.)
Fp	155 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Liquid
color	Clear yellow
Specific Gravity	1.925
Water Solubility	Insoluble in water.
Sensitive	Light Sensitive
BRN	1853970
InChIKey	KGNQDBQYEBMPFZ-UHFFFAOYSA-N
CAS DataBase Reference	352-34-1(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 1-fluoro-4-iodo-(352-34-1)
EPA Substance Registry System	p-Fluoroiodobenzene (352-34-1)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39-2637/39
RIDADR	UN2810
WGK Germany	3
TSCA	T
HazardClass	IRRITANT
HS Code	29049090

MSDS Information

Provider	Language
4-Fluoroiodobenzene	English
SigmaAldrich	English
ACROS	English
ALFA	English

1-Fluoro-4-iodobenzene Usage And Synthesis

Description	4-[18F] Fluoroiodobenzene is a versatile building block in 18F radiochemistry and is used in various transition metal-mediated C-C and C-N cross-coupling reactions. Cross-coupling reaction of 4-fluoroiodobenzene with potassium pentafluorophenyltrifluoroborate in the presence of different palladium catalysts and silver oxide in toluene has been investigated.
Chemical Properties	colorless to light yellow liquid
Uses	suzuki reaction
Uses	4-Fluoroiodobenzene was used in the preparation of fluorotriphenylene derivatives. 4-[F] Fluoroiodobenzene is a versatile building block in 18F radiochemistry and is used in various transition metal-mediated C-C and C-N cross-coupling reactions.
General Description	4-[¹⁸F] Fluoroiodobenzene is a versatile building block in ¹⁸F radiochemistry and is used in various transition metal-mediated C-C and C-N cross-coupling reactions. Cross-coupling reaction of 4-fluoroiodobenzene with potassium pentafluorophenyltrifluoroborate in the presence of different palladium catalysts and silver oxide in toluene has been investigated.

1-Fluoro-4-iodobenzene Preparation Products And Raw materials

Raw materials	1-Methylimidazole-->1-Fluoro-2-iodobenzene-->2-Methoxy-4-nitroaniline
Preparation Products	2-Fluoro-5-iodobenzaldehyde-->4-Fluorostyrene-->4-Fluorothiophenol-->4-Fluorobenzoyl chloride-->Benzene, 1,1'-(1,3-butadiyne-1,4-diyl)bis[4-fluoro--->4-Fluoro-N,N-diphenylbenzenamine-->4-Fluorobenzophenone-->4,4'-DIFLUORODIPHENYLACETYLENE-->Benzene, 2,4-dichloro-1-[[(4-fluorophenyl)thio]methyl]-

1,3-DIBROMO-5-FLUORO-2-IODOBENZENE 1,4-Diiodobenzene 1,2-DIIODO-4-FLUOROBENZENE Fluorine (Diacetoxyiodo)benzene 3-(Trifluoromethyl)benzaldehyde 2-BROMO-4-FLUORO-1-IODOBENZENE 2-CHLORO-1-FLUORO-4-IODOBENZENE,1-CHLORO-2-FLUORO-5-IODOBENZENE,3-Chloro-4-fluoro-1-iodobenzene 2-(Trifluoromethyl)benzoic acid 1-Fluoro-4-iodobenzene 5-FLUORO-2-IODOTOLUENE 2-Fluoro-5-iodotoluene Bromobenzene 2,4-Difluoroiodobenzene 2-CHLORO-4-FLUORO-1-IODOBENZENE fluoro jade 4-Bromofluorobenzene 4-Fluorophenol

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