| | ISOTHEBAINE Basic information |
| Product Name: | ISOTHEBAINE | | Synonyms: | 2,11-dimethoxy-1-hydroxyaporphine;2,11-dimethoxy-6a-alpha-aporphin-1-o;ISOTHEBAINE;(6aS)-5,6,6a,7-Tetrahydro-2,11-dimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-1-ol;4H-Dibenzo[de,g]quinolin-1-ol, 5,6,6a,7-tetrahydro-2,11-dimethoxy-6-methyl-, (6aS)- | | CAS: | 568-21-8 | | MF: | C19H21NO3 | | MW: | 311.37 | | EINECS: | | | Product Categories: | Alkaloids | | Mol File: | 568-21-8.mol |  |
| | ISOTHEBAINE Chemical Properties |
| Melting point | 203-204° | | alpha | D18 +285° in alc | | Boiling point | 451.42°C (rough estimate) | | density | 1.1699 (rough estimate) | | refractive index | 1.5000 (estimate) | | pka | 9.90±0.20(Predicted) |
| | ISOTHEBAINE Usage And Synthesis |
| Description | forms colourless prisms from EtOH and has [α]18D + 285.1 ° (EtOH). It may be
characterized as the sulphate, m.p. 120-1 °c (dec.) and also yields a diacetyl
derivative, m.p. 80-5°C. | | Definition | ChEBI: Isothebaine is an aporphine alkaloid. It derives from a hydride of an aporphine. | | References | Klee., Arch. Pharrn., 252,211 (1914)
Callow, Gulland, Haworth., J. Chern. Soc., 1444 (1929)
Kiseler, Konovalova.,J. Gen. Chern., USSR, 18,142 (1948)
Battersby, Brown.J'roc. Chern. Soc., 85 (1964)
Synthesis:
Battersby, Brown, Clements., J. Chern. Soc., 4550 (1965)
Biosyn thesis:
Battersby et al., Chern. Cornrnun., 230 (1965) |
| | ISOTHEBAINE Preparation Products And Raw materials |
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