2-AMINO-1-PHENYLETHANOL

2-AMINO-1-PHENYLETHANOL Basic information

Product Name:	2-AMINO-1-PHENYLETHANOL
Synonyms:	DL-PhenylethanolaMine;beta-Hydroxyphenethylamine, 2-Amino-1-phenylethan-1-ol;β-Hydroxyphenylethyl;alpha-(Aminomethyl)benzyl Alcohol Phenylethanolamine;231-469-1;Benzenemethanol, a-(aminomethyl)-;alpha-(Aminomethyl)benzylalcohol,tech;ALPHA-(AMINOMETHYL)BENZYL ALCOHOL
CAS:	7568-93-6
MF:	C8H11NO
MW:	137.18
EINECS:	231-469-1
Product Categories:	Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	7568-93-6.mol

2-AMINO-1-PHENYLETHANOL Chemical Properties

Melting point	56-58 °C (lit.)
Boiling point	160 °C/17 mmHg (lit.)
density	1.0630 (rough estimate)
refractive index	1.558-1.56
storage temp.	Refrigerator
solubility	Chloroform (Slightly), Methanol (Slightly)
pKa	12.04±0.35(Predicted)
form	Viscous Liquid
color	Clear yellow
Water Solubility	43.79g/L(20 ºC)
Merck	14,7287
BRN	971222
Stability:	Stable. Incompatible with oxidizing agents, acids, acid chlorides, acid anhydrides.
CAS DataBase Reference	7568-93-6(CAS DataBase Reference)
EPA Substance Registry System	Benzenemethanol, .alpha.-(aminomethyl)- (7568-93-6)

Safety Information

Hazard Codes	Xi,C
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	3259
WGK Germany	3
RTECS	DN5500000
Hazard Note	Corrosive
HazardClass	8
PackingGroup	III
HS Code	29221990

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

2-AMINO-1-PHENYLETHANOL Usage And Synthesis

Chemical Properties	white solid
Uses	2-Amino-1-phenylethanol is an intermediate in the manufacturing of pressor amines. The sulfate salt is used as topical vasoconstrictor.
Definition	ChEBI: The simplest member of the class of phenylethanolamines that is 2-aminoethanol bearing a phenyl substituent at the 1-position. The parent of the phenylethanolamine class.

2-AMINO-1-PHENYLETHANOL Preparation Products And Raw materials

Raw materials

Diethyl ether-->Lithium Aluminum Hydride-->Benzoyl chloride-->Copper(I) Cyanide-->Methanamine, N-(phenylmethylene)-1-(trimethylsilyl)--->2-(2-hydroxy-2-phenylethyl)isoindoline-1,3-dione-->2,2,2-Trifluoro-N-(2-hydroxy-2-phenylethyl)acetamide-->2-Aminoecetophenone-->2-Phenylaziridine-->(+/-)-2-CHLORO-1-PHENYLETHANOL-->2-Aminoacetophenone hydrochloride-->Benzaldehyde-->1,2-Ethanediyl, 1-phenyl- (9CI)-->Styrene oxide

Preparation Products

2-(2-chloropyrimidin-4-ylamino)-1-phenylethanol

2-({[5-(2-fluorophenyl)-2-furyl]methyl}amino)-1-phenylethanol 2-{[(3-methyl-2-thienyl)methyl]amino}-1-phenylethanol 2-[(2-Hydroxy-1,1-dimethylethyl)amino]-1-phenylethanol 2-((2-CHLORO-6-FLUOROBENZYL)AMINO)-1-PHENYLETHANOL 2-{[4-(allyloxy)-3-methoxybenzyl]amino}-1-phenylethanol 2-{[(5-methyl-2-thienyl)methyl]amino}-1-phenylethanol (2R)-2-[[(1R)-1-(Phenyl)ethyl]amino]-2-phenylethanol,(2R)-2-[[(1R)-1-Phenylethyl]amino]-2-phenylethanol (2R)-2-[[(1R)-1-(Phenyl)propyl]amino]-2-phenylethanol 2-[(3-bromobenzyl)amino]-1-phenylethanol (2R)-2-[[(1R)-1,2-Diphenylethyl]amino]-2-phenylethanol,(R)-2-[[(R)-1,2-Diphenylethyl]amino]-2-phenylethanol 2-[(2-hydroxy-2-phenylethyl)amino]-1-phenylethanol 2-{[3-(benzyloxy)benzyl]amino}-1-phenylethanol (2R)-2-[[(1R)-1-(Phenyl)pentyl]amino]-2-phenylethanol 2-[([1,1'-biphenyl]-4-ylmethyl)amino]-1-phenylethanol 2-({[5-(3-chloro-2-methylphenyl)-2-furyl]methyl}amino)-1-phenylethanol (S)-(-)-2-Phenylglycinol 2-({2-[(2-fluorobenzyl)oxy]-3-methoxybenzyl}amino)-1-phenylethanol 2-(((1-METHYL-1H-PYRROL-2-YL)METHYL)AMINO)-1-PHENYLETHANOL

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