ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Piperazine compounds 1-METHYL-4-(4-NITROPHENYL)PIPERAZINE

1-METHYL-4-(4-NITROPHENYL)PIPERAZINE

1-METHYL-4-(4-NITROPHENYL)PIPERAZINE Basic information
Product Name:1-METHYL-4-(4-NITROPHENYL)PIPERAZINE
Synonyms:1-METHYL-4-(4-NITROPHENYL)PIPERAZINE;1-Methyl-4-(4-nitrophenyl)piperazine95%;1-METHYL-4-(4-NITROPHENYL)PIPERAZINE 95%;Piperazine, 1-Methyl-4-(4-nitrophenyl)-;1-Methyl-4-(4-nitrophenyl)piperizine;1-METHYL-4-(4-NITROPHENYL)PIPERAZIN-1-IUM;1-Methyl-4-(4-nitrophenyl)piperazine,97%;1-METHYL-4-(4-NITROPHENYL)PIPERAZINE ISO 9001：2015 REACH
CAS:16155-03-6
MF:C11H15N3O2
MW:221.26
EINECS:
Product Categories:
Mol File:16155-03-6.mol
1-METHYL-4-(4-NITROPHENYL)PIPERAZINE Structure
1-METHYL-4-(4-NITROPHENYL)PIPERAZINE Chemical Properties
Melting point 109-111°C
Boiling point 369.5±37.0 °C(Predicted)
density 1.198±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka7.41±0.42(Predicted)
form Solid
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39
HazardClass IRRITANT
HS Code 29339900
MSDS Information
1-METHYL-4-(4-NITROPHENYL)PIPERAZINE Usage And Synthesis
Chemical PropertiesRed solid
Uses1-methyl-4-(4-nitrophenyl)piperazine was a reagent in the preparation of diaminopyrimidines as reversible and irreversible inhibitors of mutant EGFR tyrosine kinases for treatment of non-small-cell lung cancer. It was also used in the prepn. of disubstituted pyrimidine compds. as EGFR or/and ALK inhibitors useful in the treatment of diseases.
1-Acetyl-4-(4-nitrophenyl)piperazine 2-METHYL-2-[4-(4-NITROPHENYL)PIPERAZINO]PROPANENITRILE 1-(CHLOROACETYL)-4-(4-NITROPHENYL)PIPERAZINE ETHYL 4-(4-NITROPHENYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE 2-[4-(4-NITROPHENYL)PIPERAZINO]QUINOXALINE 5-(4-Methylpiperazin-1-yl)-2-nitroaniline 1-BENZYL-4-(4-NITROPHENYL)PIPERAZINE 2-[4-(4-NITROPHENYL)PIPERAZINO]-1-ETHANOL BUTTPARK 83\09-70 1-(4-FLUOROPHENYL)-4-(4-NITROPHENYL)PIPERAZINE 2-METHYL-2-[4-(4-NITROPHENYL)PIPERAZINO]PROPANAMIDE ETHYL 5-(3,4-DICHLOROPHENYL)-2-[4-(4-NITROPHENYL)PIPERAZINO]-1H-PYRROLE-3-CARBOXYLATE 1-methyl-4-(2-nitrophenyl)piperazine METHYL N-CYANO-4-(4-NITROPHENYL)TETRAHYDRO-1(2H)-PYRAZINECARBIMIDOTHIOATE 2-(4-methylpiperazino)-5-nitrobenzenecarbaldehyde 2-[4-(2,4-DINITROPHENYL)PIPERAZIN-1-YL]ETHANOL 5-[4-(4-NITROPHENYL)PIPERAZINO]-1H-1,2,4-TRIAZOL-3-AMINE 1-METHYL-4-(4-NITROPHENYL)PIPERAZINE
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