Bromocresol green

Bromocresol green Basic information
Product Name:Bromocresol green
Synonyms:BROMOCRESOL GREEN SULTONE FORM;BROMOCRESOL GREEN ETHANOL (50);BROMOCRESOL GREEN INDICATOR;3',3'',5',5''-TETRABROMO-3-CRESOLSULFONEPHTHALEIN;3',3'',5',5''-TETRABROMO-M-CRESOLSULFONEPHTHALEIN;3',3'',5',5''-TETRABROMO-M-CRESOLSULFONPHTHALEIN;3',3',5',5'-TETRABROMO-M-CRESOLSULFONPHTHALEIN;3,3',5,5'-TETRABROMO-M-CRESOLSULFONPHTHALEIN
CAS:76-60-8
MF:C21H14Br4O5S
MW:698.01
EINECS:200-972-8
Product Categories:Sulfonephthalein;Flavones, Flavonoids, FoodstuffsDerivatization Reagents TLC;Organic Acids, Carboxylic AcidsDerivatization Reagents;Derivatization Reagents TLC;TLC Reagents, A-C;TLC ReagentsDerivatization Reagents TLC;TLC Visualization Reagents (alphabetic sort);B;Stains and Dyes;Stains&Dyes, A to;Organics;TLC Stains;Analytical Chemistry;Indicator (pH);pH Indicators;TLC Visualization Reagents (by application);AR;76-60-8
Mol File:76-60-8.mol
Bromocresol green Structure
Bromocresol green Chemical Properties
Melting point 225 °C (dec.) (lit.)
density 0.79 g/mL at 20 °C
Fp 12 °C
storage temp. no restrictions.
solubility Solubility Sparingly soluble in water; soluble in ethanol, ether, ethyl acetate
Boiling point 626.0±55.0 °C(Predicted)
form Powder/Solid
pka4.7(at 25℃)
color Pale orange
PH3.8~5.4
PH Range3.8(YELLOW)-5.4(BLUE)
Water Solubility slightly soluble
λmax423nm, 444nm, 617nm
Merck 14,1386
BRN 372527
Stability:Stable. Incompatible with strong oxidizing agents.
Major ApplicationSol-gel matrix, fuel cells, sensors, display device, inks, paints, one-steptester for ammonia, cosmet-tester for ammonia, packaging system, textiles, cleansing products, detergents, cosmetics, diapers, identifying fresh and stale rice, monitoring fish spoilage, detecting carbohydrates, lacting acid bacteria, treating neoplasms, cancer, vaginal infection test method, drugs, dental materials
LogP7.800 (est)
CAS DataBase Reference76-60-8(CAS DataBase Reference)
EPA Substance Registry SystemBromcresol green (76-60-8)
Safety Information
Hazard Codes F,Xi,Xn
Risk Statements 11-36-67-36/37/38-20/21/22
Safety Statements 7-16-24/25-26-37/39-36
RIDADR UN 1219 3/PG 2
WGK Germany 3
RTECS SJ7456000
Autoignition Temperature399 °C
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29349990
MSDS Information
ProviderLanguage
Bromocresol green English
SigmaAldrich English
ACROS English
ALFA English
Bromocresol green Usage And Synthesis
Chemical Propertiestan to yellow crystals
UsesBromocresol Green (BCG) is a pH sensitive triphenylmethane dye useful in a variety of colorimetric detection technologies. BCG is used as a tracking dye for DNA agarose gel electrophoresis, in protein determinations and in charge-transfer complexation processes. In TLC BCG is used for visualisation of the compounds with functional groups whose pKa is below 5.0.
UsesAs indicator, pH 3.8 yellow; pH 5.4 blue-green.
UsesBromocresol Green is a pH sensitive indicator used in the growth medium for microorganisms and titrations. It is useful in various colorimetric detection studies and as an actively tracking dye for DNA agarose gel electrophoresis. It acts as an inhibitor of prostaglandin E2 transport protein. It is also used in TLC for visualizing compounds containing functional groups having pKa less than 5.
DefinitionChEBI: Bromocresolgreen is a member of benzofurans.
HazardModerately toxic.
Purification MethodsCrystallise the dye from glacial acetic acid or dissolve it in aqueous 5% NaHCO3 solution and precipitate it from the hot solution by dropwise addition of aqueous HCl. Repeat this until the UV/VIS-extinction did not increase 423nm. It is an indicator: at pH 3.81 at max (yellow) and pH 5.4 (blue-green). [Beilstein 19/3 V 460.]
Bromocresol green Preparation Products And Raw materials
Preparation Products2-AMINOCYCLOHEXANECARBONITRILE-->Sulphur yellow 2-->DIRECT YELLOW 28-->Leuco Sulphur Yellow 2
2-MERCAPTOBENZYL ALCOHOL 2,3-Dimethylbromobenzene 3-Bromobenzyl alcohol BROMOCRESOL GREEN - METHYL YELLOW SOLUTION (ETHANOL SOLN.)[MIXED INDICATOR] BROMOCRESOL GREEN, SODIUM SALT ACS GRADE Isopropyl Benzenesulfonate 2-BROMO-4-HYDROXYMETHYL-PHENOL BROMOCRESOL GREEN, ACS GRADE 2-Ethylbenzenethiol 3-Bromocumene BROMOCRESOL GREEN/METHYL RED MIXED M-cresol sulfonic acid BROMOCRESOL GREEN, INDICATOR GRADE BROMOCRESOL GREEN SOLUTION 2-(1-Methylethyl)thiophenol BROMOCRESOL GREEN - METHYL RED SOLUTION (ETHANOL SOLN.)[MIXED INDICATOR],Methyl Red - Bromocresol Green Solution (S)-1-(3-BROMOPHENYL)ETHANOL BCG Vaccine

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