2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid

2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Basic information
Product Name:2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid
Synonyms:2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid;CLOMID;CLOMIPHENE CITRATE SALT;CLOMOXIR;CLOMPHID;PERGOTIME;SEROPHENE;2-[4-(2-CHLORO-1,2-DIPHENYLETHENYL)-PHENOXY]-N,N-DIETHYLETHANAMINE CITRATE SALT
CAS:88431-47-4
MF:C14H17ClO3
MW:268.74
EINECS:200-035-3
Product Categories:
Mol File:88431-47-4.mol
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Structure
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Chemical Properties
Boiling point 411.5±35.0 °C(Predicted)
density 1.251±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka3.66±0.20(Predicted)
Safety Information
Hazard Codes T
Risk Statements 60-63
Safety Statements 53-36/37-45
WGK Germany 3
RTECS YE0875000
MSDS Information
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SigmaAldrich English
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Usage And Synthesis
Uses2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
General DescriptionClomiphene citrate, 2-[4(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine(Clomid), is used as an ovulation stimulant inwomen desiring pregnancy. Although early literature refersto clomiphene as an estrogen antagonist, it is more accuratelya SERM. Clomiphene is chemically a mixture of two geometricisomers, zuclomiphene, the cis-isomer, and enclomiphene,the trans-isomer. In animal studies, these isomershave different estrogenic actions in different tissues.Zuclomiphene appears to have weak agonist actions on alltissues studied, whereas enclomiphene has antagonist actionson uterine tissue, but agonist action on bone tissue. The actionsof clomiphene in humans are likely a composite of theactions of the two isomers.
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Preparation Products And Raw materials
Clomiphene Citrate ALPHA-HYDROXY BENZENEHEPTANOIC ACID Citric acid monohydrate Clomifene cis-clomiphene citrate 2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Citric acid

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