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| | OXONIC ACID POTASSIUM SALT Basic information |
| Product Name: | OXONIC ACID POTASSIUM SALT | | Synonyms: | 1,4,5,6-tetrahydro-4,6-dioxo-s-triazine-2-carboxylicacid,potassiumsalt;5-azaoroticacid,potassiumsalt;4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium salt, Allantoxanic acid;（OXO）Oteracil potassium;Potassium 4,6-dioxo-1H-1,3,5-triazine-2-carboxylate;Potassium s-triazine-2,4-dione-6-carboxylate;1,4,5,6-Tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylic acid potassium salt;Allantoxanic acid potassium | | CAS: | 2207-75-2 | | MF: | C4H2KN3O4 | | MW: | 195.17 | | EINECS: | 218-627-5 | | Product Categories: | Anti-cancer&immunity;oncology;Classes of Metal Compounds;K (Potassium) Compounds (excluding simple potassium salts);Typical Metal Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Anticancer | | Mol File: | 2207-75-2.mol |  |
| | OXONIC ACID POTASSIUM SALT Chemical Properties |
| Melting point | 300 °C(lit.) | | storage temp. | Inert atmosphere,2-8°C | | solubility | Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated) | | form | Powder | | color | White | | Water Solubility | Soluble in hot water. | | CAS DataBase Reference | 2207-75-2(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | RR4580000 | | HS Code | 29349990 |
| | OXONIC ACID POTASSIUM SALT Usage And Synthesis |
| Description | Oxonic acid is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats. It is a component of S-1, a mixture containing a prodrug of the antitumor agent 5-fluorouracil (5-FU; ), that suppresses the gastrointestinal toxicity of 5-FU without inhibiting its antitumor activity in rats. Formulations containing oxonic acid have been used to treat gastric, pancreatic, lung, head, neck, and breast carcinomas. | | Chemical Properties | Off-White Solid | | Uses | Antitumor effect potentiator and antitumor agent | | Uses | Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats.It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism. | | Uses | Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats. It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism. | | Definition | ChEBI: Potassium 2,6-dihydroxytriazinecarboxylate is an organic molecular entity. |
| | OXONIC ACID POTASSIUM SALT Preparation Products And Raw materials |
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