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| | PROPENTOFYLLINE Basic information |
| Product Name: | PROPENTOFYLLINE | | Synonyms: | 3,7-DIHYDRO-3-METHYL-1-(5-OXOHEXYL)-7-PROPYL-1H-PURINE-2,6-DIONE;3-METHYL-1-[5-OXOHEXYL]-7-PROPYL-XANTHINE;PROPENTOFYLLINE;3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dione, HWA-285, Albert-285, HOE-285, Hextol, Karsivan;1H-Purine-2,6-dione, 3,7-dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-;HOE-285：Hextol：Karsivan;3-Methyl-1-(5-oxohexyl)-7-propylxanthine, HWA285, 3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dione;3-Methyl-1-(5-oxohexyl)-7-propylpurine-2,6-dione | | CAS: | 55242-55-2 | | MF: | C15H22N4O3 | | MW: | 306.36 | | EINECS: | | | Product Categories: | All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 55242-55-2.mol |  |
| | PROPENTOFYLLINE Chemical Properties |
| Melting point | 64-66°C | | Boiling point | 541.4±56.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | H2O: soluble12.4mg/mL | | pka | 0.58±0.70(Predicted) | | form | solid | | color | white |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | WGK Germany | 3 | | RTECS | UO8438700 | | Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 900, 780, 1150, 940 orally; 168, 170, 180, 195 i.v.; 375, 346, 199, 196 i.p.; 450, 508, 400, 338 s.c. (Inazu) |
| | PROPENTOFYLLINE Usage And Synthesis |
| Description | Propentofylline is a nootropic indicated for cerebrovascular disorders. Other indications
currently under investigation include senile dementia, stroke and hypoxia. | | Chemical Properties | Off-White Solid | | Originator | Hoechst AG (W.Germany) | | Uses | A c-AMP phosphodiesterase inhibitor. A nerve growth factor stimulator. An adenosine transport inhibitor. A non-selective adenosine receptor antagonist. Nootropic. | | Definition | ChEBI: Propentofylline is an oxopurine. | | Brand name | Hextol | | Biochem/physiol Actions | c-AMP phosphodiesterase inhibitor; nerve growth factor stimulator; adenosine transport inhibitor; non-selective adenosine receptor antagonist. |
| | PROPENTOFYLLINE Preparation Products And Raw materials |
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