ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Phenylalanine derivatives SUC-ALA-ALA-PRO-PHE-PNA

SUC-ALA-ALA-PRO-PHE-PNA

SUC-ALA-ALA-PRO-PHE-PNA Basic information
Product Name:SUC-ALA-ALA-PRO-PHE-PNA
Synonyms:N-Succinyl-Ala-Ala-Pro-Phe 4-nitroanilide;succinyl-alanyl-alanyl-prolyl-phenylalanine-4-nitroanilide;N-succinyl-alanyl-alanyl-prolyl-phenylanaline nitroanilide;N-Succinyl-Ala-Ala-Pro-Phe-pNA, N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide;Cathepsin G Substrate I;N-SUCCINYL-L-ALANYL-L-ALANYL-L-PROLYL-L-PHENYLALANINE 4-NITROANILIDE;N-SUCCINYL-ALA-ALA-PRO-PHE-PNA;N-SUCCINYL-ALA-ALA-PRO-PHE P-NITROANILIDE
CAS:70967-97-4
MF:C30H36N6O9
MW:624.64
EINECS:
Product Categories:amino
Mol File:70967-97-4.mol
SUC-ALA-ALA-PRO-PHE-PNA Structure
SUC-ALA-ALA-PRO-PHE-PNA Chemical Properties
storage temp. -20°C
solubility DMF: 25 mg/mL, clear, light yellow
form White to off-white solid
BRN 4289896
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 10
HS Code 2933998090
MSDS Information
ProviderLanguage
SigmaAldrich English
SUC-ALA-ALA-PRO-PHE-PNA Usage And Synthesis
DescriptionSuc-AAPF-pNA is a chromogenic substrate that can be cleaved by cathepsin G (Km = 1.7 mM), subtilisins, chymotrypsin (Km = 60 μM), chymase (Km = 4 mM), and cyclophilin, but not neutrophil elastase. Release of p-nitroanilide is monitored at 405-410 nm. This substrate can be used for inhibitor screening and kinetic analysis.
UsesN-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used as a substrate to determine chymotrypsin activity.
Biochem/physiol ActionsN-succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a substrate for subtilisin and proteases.
SUC-ALA-ALA-PRO-PHE-PNA Preparation Products And Raw materials
succinimidyl-alanyl-phenylalanyl-prolyl-phenylalanine 4-nitroanilide SUC-ALA-ALA-PRO-LYS-PNA SUC-ALA-ILE-PRO-PHE-PNA N,N'-Ethylenebis(stearamide) SUC-ALA-ALA-ALA-PNA 5-METHYL-N,N-DIMETHYLTRYPTAMINE SUC-ALA-VAL-PRO-PHE-PNA SUC-ALA-GLU-PRO-PHE-PNA SUC-ALA-HIS-PRO-PHE-PNA SUC-ALA-LEU-PRO-PHE-PNA SUC-ALA-GLN-PRO-PHE-PNA SUC-ALA-LYS-PRO-PHE-PNA SUC-ALA-TRP-PRO-PHE-PNA SUC-ALA-NLE-PRO-PHE-PNA SUC-ALA-PHE-PRO-PHE-PNA SUC-SDPF-PNA SUC-LEPF-PNA SUC-ALA-ALA-PRO-PHE-PNA
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