6-Methylpyridine-3-boronic Acid

6-Methylpyridine-3-boronic Acid Basic information

Product Name:	6-Methylpyridine-3-boronic Acid
Synonyms:	(6-Methyl-3-pyridinyl)-boronic acid;2-methyl-5-pydineboronic acid;(6-METHYLPYRIDAZIN-3-YL)BORONIC ACID;2-METHYL-5-PYRIDINYLBORONIC ACID;6-METHYLPYRIDINE-3-BORONIC ACID;Boronicacid,(6-methyl-3-pyridinyl);Boronic acid, (6-methyl-3-pyridinyl)- (9CI);6-Methylpyridine-3-Boronic
CAS:	659742-21-9
MF:	C6H8BNO2
MW:	136.94
EINECS:	689-887-9
Product Categories:	blocks;BoronicAcids;Pyridines;Boronate Ester;Boronic Acid;Potassium Trifluoroborate;PYRIDINE
Mol File:	659742-21-9.mol

6-Methylpyridine-3-boronic Acid Chemical Properties

Melting point	128-130°C
Boiling point	294.7±42.0 °C(Predicted)
density	1.18±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Powder
pka	4.27±0.10(Predicted)
color	White to pale brown
Stability:	Hygroscopic
CAS DataBase Reference	659742-21-9(CAS DataBase Reference)

Safety Information

MSDS Information

6-Methylpyridine-3-boronic Acid Usage And Synthesis

Chemical Properties	White to off-white solid
Uses	suzuki reaction
Uses	6-Methylpyridine-3-boronic Acid is used in the preparation of various biologically active compound such as phosphoinositide-3-kinases (PI3K) and c-jun N-terminal kinase (JNK) inhibitors.

6-Methylpyridine-3-boronic Acid Preparation Products And Raw materials

Raw materials	Diethyl ether-->n-Butyllithium-->Nitrogen-->Triisopropyl borate-->5-Bromo-2-methylpyridine-->2-METHYL-5-PYRIDINETRIFLUOROMETHANESULF&-->3-Hydroxy-6-methylpyridine-->Bis(pinacolato)diboron
Preparation Products	2-Picoline-->BenzaMide, N-[4-Methyl-3-[[4-(6-Methyl-3-pyridinyl)-2-pyriMidinyl]aMino]phenyl]-4-[(4-Methyl-1-piperazinyl)Methyl]--->6'-Methyl-[2,3']bipyridinyl

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