2'-O-Methylcytidine

2'-O-Methylcytidine Basic information
Product Name:2'-O-Methylcytidine
Synonyms:2'-OMe-C;4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one;4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one;4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one;2'-OMe Cytidine;4-aMino-1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2-dihydropyriMidin-2-one;2'-O-Methylcytidine, >98.0%(HPLC);2'-O-Methylcytidine, >=99%
CAS:2140-72-9
MF:C10H15N3O5
MW:257.24
EINECS:2017-001-1
Product Categories:Bases & Related Reagents;Carbohydrates & Derivatives;Biochemicals and Reagents;Nucleosides, Nucleotides, Oligonucleotides;Heterocycles;Nucleotides;Nucleoside Analogs;Nucleosides
Mol File:2140-72-9.mol
2'-O-Methylcytidine Structure
2'-O-Methylcytidine Chemical Properties
Melting point 252-253 C
Boiling point 506.0±60.0 °C(Predicted)
density 1.68±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility Soluble in DMSO.
pka13.37±0.70(Predicted)
form Powder
color White to Off-white
InChIInChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
InChIKeyRFCQJGFZUQFYRF-ZOQUXTDFSA-N
SMILESOC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OC)[C@@H]1O
CAS DataBase Reference2140-72-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
2'-O-Methylcytidine Usage And Synthesis
Chemical PropertiesWhite powder
Uses2'-O-Methylcytidine is used in the preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.
UsesCytidine analog.
DefinitionChEBI: 2'-O-methylcytidine is a methylcytidine.
2'-O-Methylcytidine Preparation Products And Raw materials
Preparation Products3-METHYL URIDINE
2',3'-dideoxy-5-methylcytidine (R)-(-)-TETRAHYDROFURFURYL ALCOHOL 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-ISOBUTYRYL-2'-O-METHYLCYTIDINE,DMT-NIBU-2'-O-METHYLCYTIDINE (R)-3-(Dimethylamino)-1,2-propanediol POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE Methoxydiethylborane Anisole (Trifluoromethoxy)benzene N3-METHYLCYTIDINE (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL p-Anisic acid p-Anisidine Methoxyacetic acid p-Anisaldehyde 2'-O-Methyl-N4-Benzoyl-5'-O-DMT-Cytidine N-(2-METHOXYETHYL)UREA 2'-O-Methylcytidine N4-BENZOYL-5'-O-(DIMETHOXYTRITYL)-5-METHYL-2'-O-METHYLCYTIDINE

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