Z-SER-OBZL

Z-SER-OBZL Basic information

Product Name:	Z-SER-OBZL
Synonyms:	BENZYLOXYCARBONYL-L-SERINE BENZYL ESTER;CBZ-SER-OBZL;Cbz-L-serinebenzylester;N-alpha-Benzyloxycarbonyl-L-serine benzyl ester;Z-L-Ser-OBzl;(2S)-2-[(Benzyloxycarbonyl)amino]-3-hydroxypropionic acid benzyl ester;(2S)-2-[[(Benzyloxy)carbonyl]amino]-3-hydroxypropanoic acid benzyl ester;N-(Benzyloxycarbonyl)serine benzyl ester
CAS:	21209-51-8
MF:	C18H19NO5
MW:	329.35
EINECS:
Product Categories:
Mol File:	21209-51-8.mol

Z-SER-OBZL Chemical Properties

Melting point	83-86 °C(lit.)
Boiling point	534.5±50.0 °C(Predicted)
density	1.253
storage temp.	Sealed in dry,2-8°C
solubility	Chloroform, Methanol
form	Solid
pka	10.46±0.46(Predicted)
color	White to Pale Yellow
optical activity	[α]20/D +5°, c = 1 in chloroform
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	21209-51-8(CAS DataBase Reference)

Safety Information

Safety Statements	24/25
WGK Germany	3
HS Code	29242100

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

Z-SER-OBZL Usage And Synthesis

Chemical Properties	White to off-white powder
Uses	N-Benzyloxycarbonyl-L-serine benzyl ester is used as a building block in peptide synthesis and as a biochemical reagent. It is also used to synthesize the corresponding N-benzyloxycarbonyl-O-tert-butyl-(lor dl)-serine benzyl ester. Further, it serves as a pharmaceutical intermediate.

Z-SER-OBZL Preparation Products And Raw materials

Raw materials

L-Serine, phenylmethyl ester, 4-methylbenzenesulfonate (salt)-->N-Cbz-L-Serine-->O-Benzyl-N,N'-diisopropylisourea-->N,N-DIMETHYLFORMAMIDE DIBENZYL ACETAL-->Benzyl chloride-->p-Toluenesulfonic acid-->Benzyl chloroformate-->Benzyl alcohol-->Benzyl bromide

H-SER-OBZL·TOSOH, L-SERINE BENZYL ESTER TOSYLATE H-D-SER-OBZL·TOSOH, D-SERINE BENZYL ESTER TOSYLATE Cbz-L-Threonine benzyl ester Fmoc-L-Ser-OBzl H-SER-OBZL HCL Z-THR-ONB Z-SER(TBU)-ONB BOC-D-SER-OBZL Z-THR(TBU)-ONB Z-SER-ONB Boc-D-β-Homo-Ser(OBzl)-OH Z-THR(TBU)-OBZL Z-SER(TBU)-OBZL Boc-Ser(OBzl)-OSu BOC-Ser (Obzl) OH Z-SER-OBZL H-DL-SER-OBZL TOS-OH,H-DL-SER-OBZL TOS Z-D-SER-OBZL

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