ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Histidine derivatives 3-METHYL-L-HISTIDINE

3-METHYL-L-HISTIDINE

3-METHYL-L-HISTIDINE Basic information
Product Name:3-METHYL-L-HISTIDINE
Synonyms:3-methylhistidine;3-METHYL-L-HISTIDINE;3-METHYL-L-HISTIDINE N-HYDRATE;π-methyl-l-histidine;(2S)-2-amino-3-(3-methylimidazol-4-yl)propanoic acid;METHYL-L-HISTIDINE, 1-(RG);METHYL-L-HISTIDINE, 3-(RG);1-METHYL-L-HISTIDINE CRYSTALLINE
CAS:368-16-1
MF:C7H11N3O2
MW:169.18
EINECS:206-704-6
Product Categories:amino acid;Chiral Compound;Amino Acids
Mol File:368-16-1.mol
3-METHYL-L-HISTIDINE Structure
3-METHYL-L-HISTIDINE Chemical Properties
Melting point 248～252℃
alpha +12.0～+18.0°(20℃/D)(c=2,dil.HCl)
Boiling point 298.47°C (rough estimate)
density 1.37
refractive index 1.5950 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility PBS (pH 7.2): 10 mg/ml
form A crystalline solid
pka2.04±0.10(Predicted)
Stability:Hygroscopic
CAS DataBase Reference368-16-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
3-METHYL-L-HISTIDINE Usage And Synthesis
Chemical PropertiesWhite to off-white powder
Uses3-Methyl-L-histidine is a potential compound to be used as a treatment with pharmacological PPARα agonists to stimulate the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeleta l muscle of rodents.
DefinitionChEBI: A L-histidine derivative that is L-histidine substituted by a methyl group at position 3 on the imidazole ring.
Biochem/physiol Actions3-Methyl-L-histidine is a non-proteinogenic amino acid and an index of muscle breakdown.
3-METHYL-L-HISTIDINE Preparation Products And Raw materials
1-Methyl-L-histidine N-[(tert-Butoxy)carbonyl]-3-methyl-L-histidine N-Fmoc-N'-Trityl-L-histidine pentafluorophenyl ester BOC-HIS(3-BOM)-OSU L-Anserine 1-Phenylmethyl-L-histidine methyl ester monohydrochloride FMOC-HIS(3-ME)-OH N'-Methyl-L-histidine methyl ester PD 123319 ditrifluoroacetate N-Fmoc-N'-trityl-D-histidine (7S)-(+)-5,6,7,8-TETRAHYDRO-7-METHOXYCARBONYL-5-OXOIMIDAZA[1,5-C]PYRIMIDINE N-FMOC-3-(triphenylmethyl)-L-histidine L-ANSERINE NITRATE FMOC-HIS(3-BOM)-OH N-Boc-1-phenylmethyl-D-histidine 3-METHYL-L-HISTIDINE BOC-HIS(3-BOM)-OME HCL N-Boc-N'-benzyloxymethyl-L-histidine
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