ChemicalBook Product Catalog Biochemical Engineering Inhibitors TGF-beta / Smad TGF-beta / Smad inhibitors LDN-214117

LDN-214117

LDN-214117 Basic information
Product Name:LDN-214117
Synonyms:1-[4-[6-Methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]piperazine;LDN-214117;LDN214117;CS-1539;LDN-214117;1-(4-(6-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenyl)piperazine;Piperazine, 1-[4-[6-methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]-;LDN-214117 USP/EP/BP;LDN214117,LDN-214117,ALK2,BMP4,BMP2,Transforming growth factor beta receptors,LDN 214117,BMP6,TGF-β Receptor,diffuse intrinsic pontine glioma(DIPG),oral,ALK3,fibrodysplasia ossificans progressiva (FOP),ALK5,type I receptor kinases,ALK1,bone morphogenetic proteins (BMPs)
CAS:1627503-67-6
MF:C25H29N3O3
MW:419.52
EINECS:
Product Categories:Inhibitors
Mol File:1627503-67-6.mol
LDN-214117 Structure
LDN-214117 Chemical Properties
Boiling point 567.9±50.0 °C(Predicted)
density 1.134±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF:30.0(Max Conc. mg/mL);71.51(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.19(Max Conc. mM)
DMSO:42.67(Max Conc. mg/mL);101.7(Max Conc. mM)
Ethanol:54.0(Max Conc. mg/mL);128.72(Max Conc. mM)


form Powder
pka8.86±0.10(Predicted)
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 45
MSDS Information
LDN-214117 Usage And Synthesis
UsesLDN 214117 is a highly selective ALK2 inhibitor.
LDN-214117 Preparation Products And Raw materials
LDN-193189 HCl LDN-212320 LDN212854 LDN-193189
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