Methyl 5-chloro-6-methylpyrazine-2-carboxylate

Methyl 5-chloro-6-methylpyrazine-2-carboxylate Basic information
Pharmaceutical intermediate
Product Name:Methyl 5-chloro-6-methylpyrazine-2-carboxylate
Synonyms:5-Chloro-6-methyl-2-pyrazinecarboxylic acid methyl ester;Methyl 5-chloro-6-methylpyrazine-2-carboxylate;5-Chloro-6-methyl-pyrazine-2-carboxylic acid methyl ester;N-1H-BENZIMIDAZOL-4-YLFORMAMIDE;2-Pyrazinecarboxylic acid, 5-chloro-6-methyl-, methyl ester;Methyl 5-chloro-6-methylpyrazine-2-carboxylate ISO 9001:2015 REACH;1,4-Butanediamine,N1,N4-bis(7-chloro-5-quinolinyl)-
CAS:77168-85-5
MF:C7H7ClN2O2
MW:186.6
EINECS:
Product Categories:
Mol File:77168-85-5.mol
Methyl 5-chloro-6-methylpyrazine-2-carboxylate Structure
Methyl 5-chloro-6-methylpyrazine-2-carboxylate Chemical Properties
Melting point 40-43℃
Boiling point 260℃
density 1.314
Fp 111℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder
pka-3.86±0.10(Predicted)
color Yellow
Safety Information
HS Code 2933199090
MSDS Information
Methyl 5-chloro-6-methylpyrazine-2-carboxylate Usage And Synthesis
Pharmaceutical intermediate

The N-methyl-d-aspartate (NMDA) receptor is arguably an important signaling mechanism in the human brain and NMDA receptors play a critical role in regulating the strength of synapses, that is, in regulating synaptic plasticity. Methyl 5-chloro-6-methylpyrazine-2-carboxylate is the key materials to prepare the NMDA receptor.

UsesMethyl 5-?Chloro-?6-?methylpyrazine-?2-?carboxylate is a reactant used in the synthesis of 4,5-dihydro-5-oxo-2-pyrazinecarboxylic acid 1-oxides.
Methyl 5-chloro-6-methylpyrazine-2-carboxylate Preparation Products And Raw materials
Raw materials2-Pyrazinecarboxylic acid, 4,5-dihydro-6-Methyl-5-oxo-, Methyl ester-->5-Methyl-6-oxo-1,6-dihydropyrazine-2,3-dicarbonitrile

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