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| | N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Basic information |
| Product Name: | N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine | | Synonyms: | SHIKAWA'S REAGENT;N,N-DIETHYL-1,1,2,3,3,3-HEXAFLUOROPROPYLAMINE;Ishikawa's Reagent, 1-(Diethylamino)-1,1,2,3,3,3-hexafluoropropane;N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine, 40% solution in THF;Ishikawa's Reagent, technical, 90%;MEC-81;1,1,2,3,3,3-HEXAFLUORO-1-DIETHYLAMINO-PROPAN;1,1,2,3,3,3-HEXAFLUORO-1-DIETHYLAMINOPROPANE | | CAS: | 309-88-6 | | MF: | C7H11F6N | | MW: | 223.16 | | EINECS: | 628-698-8 | | Product Categories: | Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Fluorination;Halogenation;Synthetic Organic Chemistry;Chemical Synthesis;Fluorination Reagents;Synthetic Reagents | | Mol File: | 309-88-6.mol |  |
| | N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Chemical Properties |
| Boiling point | 56-57 °C (lit.) | | density | 1.230 g/mL at 25 °C (lit.) | | refractive index | 1.3460 | | Fp | 56-57°C/58mm | | storage temp. | Flammables area | | solubility | soluble in Acetone,Ether | | pka | 1.50±0.70(Predicted) | | form | Liquid | | color | Clear colorless to yellow | | Specific Gravity | 1.230 | | Merck | 14,5108 | | CAS DataBase Reference | 309-88-6(CAS DataBase Reference) | | EPA Substance Registry System | N,N-Diethyl-2H-perfluoropropanamine (309-88-6) |
| Hazard Codes | C | | Risk Statements | 10-34 | | Safety Statements | 16-26-36/37/39-45 | | RIDADR | 3267 | | WGK Germany | 3 | | Hazard Note | Corrosive | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29211999 |
| | N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Usage And Synthesis |
| Chemical Properties | Clear colorless to yellow liquid | | Uses | Reactant for:
- Friedel-Crafts type arylation of hydrofluorocarbons
- Microbial hydroxylation of antibiotics
- Electrochemical fluorination of trialkylamines and tetraalkylammonium salts
- Fluorination of pyrethroides
Reactant for synthesis of:
- γ-Hydroxy-α-fluoro-α-trifluoromethylcarboxamide
- Florfenicol and thiamphenicol
| | Uses | Fluorinating agent. | | Uses | Demonstrates utility in fluorination.7 | | General Description | GC analysis includes Et2NCF=CFCF3 (two isomers), both of which are active fluorinating agents. |
| | N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Preparation Products And Raw materials |
| Raw materials | 1-Propen-1-amine, N,N-diethyl-1,2,3,3,3-pentafluoro--->N,N-DIETHYL-2,3,3,3-TETRAFLUOROPROPIONAMIDE-->1,2-DIBROMOHEXAFLUOROPROPANE-->Diethylamine-->Hexafluoropropylene |
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