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| | 2-Adamantanamine hydrochloride Basic information |
| Product Name: | 2-Adamantanamine hydrochloride | | Synonyms: | tricyclo(3.3.1.1(sup3,7))decan-2-amine,hydrochloride;2-ADAMANTYLAMINE HYDROCHLORIDE;2-ADAMANTANAMINE HYDROCHLORIDE;2-AMINOADAMANTANE HYDROCHLORIDE;2-Adamantamine hydrochloride 98+%;tricyclo(3.3.1.13.7)dec-2-ylamine hydrochloride;adamantan-2-amine hydrochloride;2-ADAMANTANAMINE HCL | | CAS: | 10523-68-9 | | MF: | C10H18ClN | | MW: | 187.71 | | EINECS: | 234-074-2 | | Product Categories: | Adamantanes;Adamantane derivatives | | Mol File: | 10523-68-9.mol |  |
| | 2-Adamantanamine hydrochloride Chemical Properties |
| Melting point | >300 °C(lit.) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | | form | Crystalline Powder | | color | White | | Water Solubility | soluble | | BRN | 4297901 | | CAS DataBase Reference | 10523-68-9(CAS DataBase Reference) |
| | 2-Adamantanamine hydrochloride Usage And Synthesis |
| Chemical Properties | white crystalline powder | | Uses | 2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2?-(carboxymethoxime)-olivomycin I. The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. | | Uses | 2-Adamantanamine Hydrochloride can be used to prepare CD73 inhibitors to treat CD73-associated diseases, including cancer and immune-related disorders. | | General Description | The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied. | | Purification Methods | The free amine in Et2O, liberated by the action of alkali in H2O, is dried over KOH, filtered, evaporated and sublimed at 110o/12torr, m 230-236o. The base is dissolved in EtOH, sufficient ethanolic HCl is added dropwise and crystallised by the addition of Et2O. Dry it in vacuo. [Stetter et al. Justus Liebigs Ann Chem 658 151 1962]. |
| | 2-Adamantanamine hydrochloride Preparation Products And Raw materials |
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