Benzyloxyacetyl chloride

Benzyloxyacetyl chloride Basic information
Product Name:Benzyloxyacetyl chloride
Synonyms:BENZYLOXYACETYL CHLORIDE;Benzyloxyacetyl chloride ,95%;(Benzyloxy)acetic acid chloride;2-(Benzyloxy)acetic acid chloride;Benzyloxyacetic acid chloride;Acetyl chloride, 2-(phenylMethoxy)-;Benzyloxyacetyl chloride 95%;2-(Phenylmethoxy)-acetyl chloride
CAS:19810-31-2
MF:C9H9ClO2
MW:184.62
EINECS:629-534-8
Product Categories:Acid Halides;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Organic Building Blocks;Pyridines;Acid Halides;Carbonyl Compounds;Carboxylic
Mol File:19810-31-2.mol
Benzyloxyacetyl chloride Structure
Benzyloxyacetyl chloride Chemical Properties
Melting point 120 °C (decomp)
Boiling point 84-87 °C/0.4 mmHg (lit.)
density 1.17 g/mL at 25 °C (lit.)
refractive index n20/D 1.523(lit.)
Fp >230 °F
storage temp. 2-8°C
form Powder or Cyrstals
color White
Water Solubility Reacts with water.
Sensitive Moisture Sensitive
BRN 1947363
CAS DataBase Reference19810-31-2(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 14-34
Safety Statements 26-36/37/39-45
RIDADR UN 3265 8/PG 2
WGK Germany 3
10-19
HazardClass 8
PackingGroup III
HS Code 29189900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Benzyloxyacetyl chloride Usage And Synthesis
Chemical PropertiesColorless to yellow liquid
UsesBenzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.
UsesCommonly employed reagent for asymmetric synthesis of β-lactams.1,2
Benzyloxyacetyl chloride Preparation Products And Raw materials
Preparation Productsmethyl 2-(benzyloxy)acetate
Phenoxyacetyl chloride Methoxyacetyl chloride Bromoacetyl chloride (-)-MENTHOXYACETYL CHLORIDE 4-Methoxybenzylchloride BENZYL 2-CHLOROETHYL ETHER BENZYLOXYACETALDEHYDE 2-Chloroethyl ethyl ether Acetyl chloride Zinc chloride Chloroacetyl chloride Phenylacetyl chloride Oxalyl chloride Benzyloxyacetyl chloride Thionyl chloride Acetoxyacetyl chloride Benzyloxyacetic acid 2-​[[(2-​ethylphenyl)​(2-​hydroxyethyl)​amino]​methyl]​-​3,​3-​difluoro-Propanenitrile

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