3-methylpseudouridine

3-methylpseudouridine Basic information
Uses
Product Name:3-methylpseudouridine
Synonyms:3-methylpseudouridine;NSC 363818;3-Methyl-5-beta-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione;3-Methylpsedouridine;N3-Methylpseudouridine;3-Methylpseudouridine, RNA modified nucleoside, m3?, Pseudouridine impurity;5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-methylpyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, 3-methyl-5-β-D-ribofuranosyl-
CAS:81691-06-7
MF:C10H14N2O6
MW:258.22796
EINECS:
Product Categories:Pharmaceutical
Mol File:81691-06-7.mol
3-methylpseudouridine Structure
3-methylpseudouridine Chemical Properties
density 1.576±0.06 g/cm3(Predicted)
pka9.88±0.10(Predicted)
Safety Information
MSDS Information
3-methylpseudouridine Usage And Synthesis
Uses3-Methylpseudouridine is used for increasing viability or longevity of organ or organ explant using modified mRNAs for proteins essential for organ survival.
Uses3-Methylpseudouridine (CAS# 81691-06-7) is used for increasing viability or longevity of organ or organ explant using modified mRNAs for proteins essential for organ survival.
DefinitionChEBI: 3-Methylpseudouridine is a carbohydrate derivative and a nucleobase-containing molecular entity.
Synthesisψ-Uridine was trimethylsilylated and the crude product was treated with acetyl chloride, to give the 1-acetyl derivative (3). Crude 3 was methylated with dimethoxymethyldimethylamine and then saponified, to give crystalline 3-methyl-ψ-uridine in 82% overall yield.

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